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8555 CDC14B

8555

CDC14B

cell division cycle 14B

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 14B

研究结论

Date Results Publications
2021-02-06 13:53:00 MiR-1247-5p Functions as a Tumor Suppressor in Human Astroglioma Cells by Targeting CDC14B. 32366555
2019-10-05 10:12:00 miR-1225 targets CDC14B 3'-UTR and recovery of CDC14B expression counteracted the suppressive influence of miR-1225 on laryngeal cancer cells 30138106
2018-10-27 12:15:00 The authors found a significant association between the localization of RET mutations and the expression of three genes: NNAT (suggested to be a tumour suppressor gene), CDC14B (involved in cell cycle control) and NTRK3 (tyrosine receptor kinase that undergoes rearrangement in papillary thyroid cancer) in patients with medullary thyroid cancer. 28181547
2016-04-09 10:05:00 hCdc14B promotes reactivation of rDNA transcription by dephosphorylating TAFI110. SIRT1 becomes transiently enriched in nucleoli at the onset of mitosis. SIRT1 deacetylates TAFI68 destabilizing SL1 binding to the rDNA promoter 26023773
2014-05-03 11:27:00 CDC14B expression is downregulated in clear cell renal carinoma, suggesting its role in renal carcinogenesis 24619757

名称对应

Type IDs
Synonymous CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Gene
UniProtKB-ID: CC14B_HUMAN
UniprotKB: O60729
UniParc: UPI0000072924, UPI00004A25D9, UPI000004DC19, UPI0000D618CE, UPI0000072B7E
EMBL: AY675321, AL133477, AK126388, AF023158, AF064104, AF064105, AL353578, CH471174, EF611343
Ensembl: ENSG00000081377
KO: hsa:8555
Nucleutide sequences
EMBL-CDS: BAG54321.1, AAT70726.1, AAC16661.1, AAC16662.2, EAW92658.1, EAW92659.1, AAB88293.1, ABR12627.1
Ensembl_TRS: ENST00000474602, ENST00000463569, ENST00000375241, ENST00000375240, ENST00000375242
Protein sequencees
Ensembl_PRO: ENSP00000364389, ENSP00000417897, ENSP00000420572, ENSP00000364390, ENSP00000364388
RefSeq: XP_016870730.2, NP_001338497.1, XP_011517450.2, XP_011517458.2, NP_003662.1, NP_001338496.1, XP_011517455.2, XP_011517454.2, XP_011517461.2, XP_011517449.2, XP_011517451.2, NP_001338498.1, XP_011517453.2, XP_016870731.1, XP_016870736.1, XP_016870733.1, NP_001338499.1, NP_201588.1, XP_016870738.1, XP_016870729.2, XP_016870734.1, XP_016870737.1, NP_001070649.1
Others
UniRef100: UniRef100_O60729
UniRef90: UniRef90_O60729
UniRef50: UniRef50_O60729
UniGene: Hs.40582
CCDS: CCDS6722.1, CCDS43853.1, CCDS87662.1, CCDS6721.1

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