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855498 ATG4

855498

ATG4

cysteine protease ATG4

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition cysteine protease ATG4

研究结论

Date Results Publications
2018-01-27 11:14:00 findings showt Atg4 is recruited onto autophagosomal membranes by direct binding to Atg8 via two evolutionarily conserved Atg8 recognition sites; propose a model where Atg4 activity on autophagosomal membranes depends on cooperative action of at least 2 sites within Atg4, in which one functions as a constitutive Atg8 binding module, while the other has a preference toward phosphatidylethanolamine-bound Atg8 28330855
2017-12-09 12:04:00 Data show that phosphorylation by Atg1 inhibits Atg4 at autophagosome formation sites. 28821724
2017-09-30 10:36:00 Results provide evidence that Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae. 28704456
2015-09-26 19:56:00 fine-tuning of Atg4 activity depending on the intracellular redox state may regulate autophagosome formation 25483965

名称对应

Type IDs
Synonymous APG4, AUT2
Gene
UniProtKB-ID: ATG4_YEAST
UniprotKB: P53867
UniParc: UPI0000168A03
EMBL: Z71499, BK006947, U20390, Z69381
EnsemblGenome: YNL223W
KO: sce:YNL223W
Nucleutide sequences
EMBL-CDS: AAA86498.1, CAA93375.1, CAA96126.1, DAA10333.1
Gene_ORFName: N1274
EnsemblGenome_TRS: YNL223W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL223W
RefSeq: NP_014176.2
Others
UniRef100: UniRef100_A6ZRL7
UniRef90: UniRef90_A6ZRL7
UniRef50: UniRef50_A6ZRL7

全选

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研究热度

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