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855477 SUI1

855477

SUI1

translation initiation factor eIF1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition translation initiation factor eIF1

研究结论

Date Results Publications
2019-10-19 12:21:00 eIF2beta or eIF1 substitutions disrupting these contacts increase initiation at UUG codons, and compound substitutions also derepress translation of GCN4, indicating slower TC recruitment. 30576497
2018-08-25 10:51:00 Thus, electrostatic interactions involving the eIF1A N-terminal tail stabilize the closed conformation and promote utilization of suboptimal start codons. 29206102
2018-08-18 12:05:00 eIF1 Loop 2 interactions with control the accuracy of start codon selection by the scanning preinitiation complex. 29666249
2014-03-22 11:01:00 The GTPase-activating protein eIF5 and beta-subunit of eIF2 promote transcriptional accuracy by controlling eIF1 dissociation and the stability of ternary complex binding to the preinitiation complex. 24335188
2013-11-30 11:20:00 substituting Lys-60 in helix alpha1, or either Lys-37 or Arg-33 in beta-hairpin loop-1, impairs binding of yeast eIF1 to 40 S.eIF1A complexes in vitro, and it confers increased initiation at UUG codons (Sui(-) phenotype) 23893413

名称对应

Type IDs
Synonymous MOF2, RFR1
Gene
UniProtKB-ID: SUI1_YEAST
UniprotKB: P32911
UniParc: UPI0000053147
EMBL: Z71520, BK006947, X96722, M77514
EnsemblGenome: YNL244C
KO: sce:YNL244C
Nucleutide sequences
EMBL-CDS: DAA10315.1, AAA35131.1, CAA65499.1, CAA96150.1
Gene_ORFName: N0905
EnsemblGenome_TRS: YNL244C_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL244C
RefSeq: NP_014155.1
Others
UniRef100: UniRef100_P32911
UniRef90: UniRef90_P32911
UniRef50: UniRef50_P32911

全选

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研究热度

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