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855457 PDR17

855457

PDR17

phosphatidylinositol transporter

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition phosphatidylinositol transporter

研究结论

Date Results Publications
2020-06-13 10:08:00 PstB2p (PDR17) forms a homodimer but exists as a 1:1 heterodimer in the presence of Pbi1p. Phosphatidylserine binding to PstB2p triggers the dissociation of the PstB2p-Pbi1p complex. 31351588
2020-03-07 12:47:00 Mutated phosphatidylinositol (PI) transfer protein Pdr17E237A, K269A is defective in high affinity PI binding. Pdr17p binds a sterol in addition to PI in an assay using permeabilized cells. PI binding defective Pdr17E237A, K269A retains the ability to transfer PI in vitro. 31302248
2014-04-26 12:33:00 model predicts that this process involves an acceptor membrane complex containing the C2 domains of Psd2p, PstB2p, and Pbi1p that ligate to Scs2p and phosphatidic acid present in the donor membrane 24366873
2013-11-02 11:04:00 Overexpression of PDR17 complemented the azole susceptible phenotype of the pdr16Delta strain and corrected the enhanced sterol alterations in pdr16Delta cells in the presence of azoles. 23606207

名称对应

Type IDs
Synonymous ISS1, SFH4
Gene
UniProtKB-ID: PDR17_YEAST
UniprotKB: P53844
UniParc: UPI000013BA59
EMBL: BK006947, AY692928, X92494, Z71540
EnsemblGenome: YNL264C
KO: sce:YNL264C
Nucleutide sequences
EMBL-CDS: CAA63233.1, AAT92947.1, DAA10295.1, CAA96171.1
Gene_ORFName: N0815
EnsemblGenome_TRS: YNL264C_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL264C
RefSeq: NP_014135.1
Others
UniRef100: UniRef100_P53844
UniRef90: UniRef90_P53844
UniRef50: UniRef50_P53844

全选

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研究热度

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