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855449 SEC2

855449

SEC2

guanine nucleotide exchange factor SEC2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition guanine nucleotide exchange factor SEC2

研究结论

Date Results Publications
2019-10-26 11:37:00 Hsp110 (Sse1 and Sse2) associates with the 19S regulatory particle of the 26S proteasome and interacts with Hsp70 (Ssa1, Ssa2) to facilitate the delivery of Hsp70 substrates for proteasomal degradation. 29507114
2016-09-24 10:19:00 Yck1p and Yck2p phosphorylate sites within the Sec2p Ypt32p/Sec15p binding region and in doing so promote binding of Sec2p to Sec15p and inhibit binding to Ypt32p. 26700316
2016-01-23 11:23:00 Structural investigation of the Sec4p-Sec2p complex reveals the role of the Sec2p coiled-coil domain in facilitating the fast kinetics of the exchange reaction. 26263895
2014-02-22 11:46:00 The phosphorylation state of Sec2p can direct a switch in its regulatory binding partners that facilitates maturation of the secretory vesicle and helps to promote the directionality of vesicular transport. 24248333
2011-01-01 10:54:00 Data suggest that following autophagy induction the function of Sec2 and Sec4 are diverted to direct membrane flow to autophagosome formation. 20444978

名称对应

Type IDs
Gene
UniProtKB-ID: SEC2_YEAST
UniprotKB: P17065
UniParc: UPI000013574D
EMBL: Z71548, X52147, BK006947
EnsemblGenome: YNL272C
KO: sce:YNL272C
Nucleutide sequences
EMBL-CDS: CAA36395.1, CAA96180.1, DAA10288.1
Gene_ORFName: N0641
EnsemblGenome_TRS: YNL272C_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL272C
RefSeq: NP_014127.1
Others
UniRef100: UniRef100_P17065
UniRef90: UniRef90_P17065
UniRef50: UniRef50_P17065

全选

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研究热度

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