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855448 TOF1

855448

TOF1

Tof1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Tof1p

研究结论

Date Results Publications
2021-01-02 12:53:00 Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress. 33166393
2019-08-24 11:17:00 Results suggest that the Tof1 replicative function exerts its protective role when fork stalling is severe enough to require extra stabilization, such as at long expanded CAG repeats. 30476303
2017-12-16 11:46:00 Phosphorylation regulates the recruitment and retention of Tof1-Csm3 by the replisome and that this complex antagonizes the Rrm3 helicase, thereby promoting replication fork arrest. 27298353
2016-04-30 12:03:00 although fork rotation and precatenation facilitate unwinding in hard-to-replicate contexts, they intrinsically disrupt normal chromosome duplication and are therefore restricted by Timeless/Tipin 26240319
2015-01-17 12:04:00 Tof1, Mrc1 and Csm3 complex, inhibits CAG.CTG repeat instability. 18321795

名称对应

Type IDs
Gene
UniProtKB-ID: TOF1_YEAST
UniprotKB: P53840
UniParc: UPI000013BA64
EMBL: Z71549, BK006947
EnsemblGenome: YNL273W
KO: sce:YNL273W
Nucleutide sequences
EMBL-CDS: DAA10287.1, CAA96181.1
Gene_ORFName: N0636
EnsemblGenome_TRS: YNL273W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL273W
RefSeq: NP_014126.1
Others
UniRef100: UniRef100_P53840
UniRef90: UniRef90_P53840
UniRef50: UniRef50_P53840

全选

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研究热度

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