Type | Description |
---|---|
Definition | Hch1p |
Date | Results | Publications |
---|---|---|
2018-11-24 11:03:00 | Phosphorylation of human Hsp90alpha at the highly conserved tyrosine (Y) 627 affects it conformation and function. Y627 is not phosphorylated in yeast, but study demonstrated that the non-conserved yeast co-chaperone, Hch1, modifies yeast Hsp90 (Hsp82) through Y606E phosphomimetic mutation raising the possibility that this post-translational modification in higher eukaryotes represents an evolutionary substitution for ... | 28537252 |
2014-07-12 11:00:00 | The work here suggests that both Hch1p and Aha1p regulate Hsp90 function through interaction with the catalytic loop but do so in different ways. | 24726918 |
2013-05-11 12:40:00 | The co-chaperone Hch1 regulates Hsp90 function differently than its homologue Aha1 and confers sensitivity to yeast to the Hsp90 inhibitor NVP-AUY922. | 23166640 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
HCH1_YEAST
UniprotKB:
P53834
UniParc:
UPI000013BA6E
EMBL:
BK006947,
Z71557
EnsemblGenome:
YNL281W
KO:
sce:YNL281W
|
Nucleutide sequences |
EMBL-CDS:
DAA10279.1,
CAA96193.1
Gene_ORFName:
N0589
EnsemblGenome_TRS:
YNL281W_mRNA
|
Protein sequencees |
EnsemblGenome_PRO:
YNL281W
RefSeq:
NP_014118.1
|
Others |
UniRef100:
UniRef100_P53834
UniRef90:
UniRef90_P53834
UniRef50:
UniRef50_P53834
|
排名 | 科研单位 | 文献 |
---|---|---|
1 |
University of Toronto |
4 |
2 |
University of Alberta |
4 |
3 |
University of Idaho |
3 |
4 |
University of Minnesota-Twin Cities |
2 |
5 |
Howard Hughes Medical Institute |
2 |
排名 | 研究人员 | 文献 |
---|---|---|
1 |
Charles Boone |
4 |
2 |
Paul LaPointe |
4 |
3 |
Yiqun Chen |
3 |
4 |
Raamesh Deshpande |
3 |
5 |
Hongwei Zhu |
3 |