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855418 CLA4

855418

CLA4

serine/threonine protein kinase CLA4

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition serine/threonine protein kinase CLA4

研究结论

Date Results Publications
2017-09-16 12:19:00 Upon arrival at the bud cortex, Vac17 is phosphorylated by Cla4. Cla4-dependent phosphorylation is required for the ubiquitylation and subsequent degradation of Vac17 and the release of the vacuole from Myo2. 28495836
2010-02-15 11:25:00 Results suggest that the Cdc42 effectors Ste20, Cla4, and Skm1 translocate into the nucleus, where they modulate expression of sterol uptake genes via Sut1, thereby controlling sterol homeostasis. 19793923
2010-01-21 00:00:00 Ste20p & Cla4p may function as negative modulators of sterol biosynthesis. Cla4p has negative effect on steryl ester formation. Ste20p and Cla4p may regulate cell polarity in part through the modulation of sterol homeostasis. 20050180
2010-01-21 00:00:00 Cla4 and Ste20 play roles in cell segregation and the degradation of Vac17. 19218422
2010-01-21 00:00:00 Our findings suggest that Cla4-dependent phosphorylation promotes the initial association of Lte1 with Ras at the bud cortex and that Ras is required to stabilize phosphorylated forms of Lte1 at the bud cortex. 15917658

名称对应

Type IDs
Synonymous ERC10
Gene
UniProtKB-ID: CLA4_YEAST
UniprotKB: P48562
UniParc: UPI0000127A83
EMBL: BK006947, U23084, Z71574, X82499
EnsemblGenome: YNL298W
KO: sce:YNL298W
Nucleutide sequences
EMBL-CDS: AAC49100.1, DAA10262.1, CAA57879.1, CAA96216.1
Gene_ORFName: N0450
EnsemblGenome_TRS: YNL298W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL298W
RefSeq: NP_014101.1
Others
UniRef100: UniRef100_P48562
UniRef90: UniRef90_P48562
UniRef50: UniRef50_P48562

全选

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研究热度

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