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8554 PIAS1

8554

PIAS1

protein inhibitor of activated STAT 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein inhibitor of activated STAT 1

研究结论

Date Results Publications
2020-10-03 12:26:00 The SUMO3 modification of PIAS1 is also required for androgen receptor ubiquitination and degradation by recruiting ubiquitin E3 ligase MDM2. 31752909
2020-08-15 19:05:00 PIAS genes as disease markers in bipolar disorder. 30861611
2020-07-25 11:20:00 The current investigation highlights the role of PIAS1 downregulation in the evolution of graft rejection and potentiates this gene as a predictive marker for transplant fate. 31870601
2020-04-25 10:49:00 The small ubiquitin-like modifier (SUMO) protein is an ubiquitin-like (UBL) protein that is highly dynamic and can reversibly target lysine residues on a wide range of proteins involved in several essential cellular events, including protein translocation and degradation.Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility. 32047143
2019-08-17 12:32:00 PIAS1expression of PIAS1 gene was increased in patients with MS compared to healthy subjects; also, there was a significant correlation between the expression of PIAS1 and PIAS2 genes with disease severity of multiple sclerosis 31084243

名称对应

Type IDs
Synonymous DDXBP1, GBP, GU/RH-II, ZMIZ3
Gene
UniProtKB-ID: PIAS1_HUMAN, Q1XBU8_HUMAN
UniprotKB: O75925, Q1XBU8
UniParc: UPI00006EB4EE, UPI0000140A60, UPI0001A93379, UPI0000131A8C
EMBL: CH471082, U78524, AF077951, BC118587, AF167160, AY826819, AC107871, BC121797, AC135628, AK314515, AK094641, FJ997900
Ensembl: ENSG00000033800
KO: hsa:8554
Nucleutide sequences
EMBL-CDS: AAB58488.1, BAG52901.1, AAC36702.1, AAI18588.1, BAG37114.1, AAI21798.1, AAD49722.1, ACR77525.1, AAX18639.1, EAW77805.1
Gene_ORFName: hCG_23811
Ensembl_TRS: ENST00000545237, ENST00000249636
Protein sequencees
Ensembl_PRO: ENSP00000249636, ENSP00000438574
RefSeq: XP_016878179.1, NP_001307616.1, XP_016878180.1, XP_016878178.1, XP_011520428.1, XP_024305862.1, XP_016878177.1, XP_011520429.1, NP_057250.1
Others
UniRef100: UniRef100_O75925
UniRef90: UniRef90_O75925
UniRef50: UniRef50_O75925
UniGene: Hs.162458
CCDS: CCDS45290.1, CCDS81902.1

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