Type | Description |
---|---|
Definition | protein inhibitor of activated STAT 1 |
Date | Results | Publications |
---|---|---|
2020-10-03 12:26:00 | The SUMO3 modification of PIAS1 is also required for androgen receptor ubiquitination and degradation by recruiting ubiquitin E3 ligase MDM2. | 31752909 |
2020-08-15 19:05:00 | PIAS genes as disease markers in bipolar disorder. | 30861611 |
2020-07-25 11:20:00 | The current investigation highlights the role of PIAS1 downregulation in the evolution of graft rejection and potentiates this gene as a predictive marker for transplant fate. | 31870601 |
2020-04-25 10:49:00 | The small ubiquitin-like modifier (SUMO) protein is an ubiquitin-like (UBL) protein that is highly dynamic and can reversibly target lysine residues on a wide range of proteins involved in several essential cellular events, including protein translocation and degradation.Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility. | 32047143 |
2019-08-17 12:32:00 | PIAS1expression of PIAS1 gene was increased in patients with MS compared to healthy subjects; also, there was a significant correlation between the expression of PIAS1 and PIAS2 genes with disease severity of multiple sclerosis | 31084243 |
Type | IDs |
---|---|
Synonymous | DDXBP1, GBP, GU/RH-II, ZMIZ3 |
Gene |
UniProtKB-ID:
PIAS1_HUMAN,
Q1XBU8_HUMAN
UniprotKB:
O75925,
Q1XBU8
UniParc:
UPI00006EB4EE,
UPI0000140A60,
UPI0001A93379,
UPI0000131A8C
EMBL:
CH471082,
U78524,
AF077951,
BC118587,
AF167160,
AY826819,
AC107871,
BC121797,
AC135628,
AK314515,
AK094641,
FJ997900
Ensembl:
ENSG00000033800
KO:
hsa:8554
|
Nucleutide sequences |
EMBL-CDS:
AAB58488.1,
BAG52901.1,
AAC36702.1,
AAI18588.1,
BAG37114.1,
AAI21798.1,
AAD49722.1,
ACR77525.1,
AAX18639.1,
EAW77805.1
Gene_ORFName:
hCG_23811
Ensembl_TRS:
ENST00000545237,
ENST00000249636
|
Protein sequencees |
Ensembl_PRO:
ENSP00000249636,
ENSP00000438574
RefSeq:
XP_016878179.1,
NP_001307616.1,
XP_016878180.1,
XP_016878178.1,
XP_011520428.1,
XP_024305862.1,
XP_016878177.1,
XP_011520429.1,
NP_057250.1
|
Others |
UniRef100:
UniRef100_O75925
UniRef90:
UniRef90_O75925
UniRef50:
UniRef50_O75925
UniGene:
Hs.162458
CCDS:
CCDS45290.1,
CCDS81902.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员