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855393 LEM3

855393

LEM3

Lem3p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Lem3p

研究结论

Date Results Publications
2012-05-12 10:04:00 Data show that Lem3-Dnf1/Dnf2 complex regulates the polar Cdc42 dynamics and phosphatidylserine distribution. 22344035
2011-05-21 10:33:00 Import of choline phospholipids into S. cerevisiae DeltaLem3 vector is partially reconstituted by human TMEM30a and by Lem3p-TMEM30a chimeras, showing that the proteins are orthologous. 21289302
2010-01-21 00:00:00 The ELM pathway for lyso-PtdEtn requires the action of Dnf1p and Dnf2p and their requisite beta-subunit, Lem3p, for the active uptake of lyso-PtdEtn. In addition, Ale1p, mediates the acylation of the imported lysolipid to form PtdEtn. 17951629
2010-01-21 00:00:00 Mutations in impaired growth in that medium, indicating that Lem3p is involved in the utilization of extracellular phosphatidylcholine (PC) with short acyl chains. 19270412
2010-01-21 00:00:00 Lem3p-Dnf1p complex may play a role distinct from its plasma membrane aminophospholipid translocase activity when it substitutes for the Cdc50p-Drs2p complex, its redundant partner in the endosomal/trans-Golgi network compartments. 16600184

名称对应

Type IDs
Synonymous BRE3, ROS3
Gene
UniProtKB-ID: LEM3_YEAST
UniprotKB: P42838
UniParc: UPI000013BA94
EMBL: Z71599, Z46259, BK006947
EnsemblGenome: YNL323W
KO: sce:YNL323W
Nucleutide sequences
EMBL-CDS: DAA10239.1, CAA86374.1, CAA96254.1
Gene_ORFName: N0333
EnsemblGenome_TRS: YNL323W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL323W
RefSeq: NP_014076.1
Others
UniRef100: UniRef100_P42838
UniRef90: UniRef90_P42838
UniRef50: UniRef50_P42838

全选

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研究热度

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