| Type | Description |
|---|---|
| Definition | U2 snRNP complex subunit HSH155 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 12:11:00 | Results show the identification of a potential UHM-ULM protein domains interaction between Cus2 and Hsh155. Amino acid substitutions in the ULM of Hsh155 abolish the binding in vivo. | 31110137 |
| 2017-12-09 11:42:00 | Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress. | 28978642 |
| 2017-09-16 10:21:00 | different HSH155 alleles elicit disparate effects on splicing: some increase the fidelity of BS selection while others decrease fidelity. Our data support a model wherein conformational changes in SF3b1 promote U2 association with the BS independently of the action of the DEAD-box ATPase Prp5. We propose that SF3b1 functions to stabilize weak U2/BS duplexes to drive spliceosome assembly and splicing | 28062854 |
| 2017-07-01 11:54:00 | show here that hsh155 mutant alleles in Saccharomyces cerevisiae, counterparts of SF3B1 mutations frequently found in cancers, specifically change splicing of suboptimal BS pre-mRNA substrates | 28087715 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SF3B1_YEAST
UniprotKB:
P49955
UniParc:
UPI00000531EC
EMBL:
Z49704,
BK006946
EnsemblGenome:
YMR288W
KO:
sce:YMR288W
|
| Nucleutide sequences |
EMBL-CDS:
DAA10189.1,
CAA89786.1
Gene_ORFName:
YM8021.14
EnsemblGenome_TRS:
YMR288W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YMR288W
RefSeq:
NP_014015.1
|
| Others |
UniRef100:
UniRef100_P49955
UniRef90:
UniRef90_P49955
UniRef50:
UniRef50_P49955
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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