| Type | Description |
|---|---|
| Definition | ATP-dependent DNA helicase YKU70 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 12:53:00 | Ku complex prevents meiotic recombination in the elimination of MRX activity. | 30940321 |
| 2019-06-01 12:28:00 | DNA with ends occluded by the DNA end-joining factor Ku70-Ku80 becomes a suitable substrate for long-range 5'-3' resection when a nick is introduced at a locale proximal to one of the Ku-bound DNA ends. | 30224356 |
| 2017-09-09 10:47:00 | Repair of UV-induced DNA lesions in Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction. | 28334768 |
| 2017-05-13 14:52:00 | the yKu-distal portion of telomeres is bound by Rap1, which in turn reduces the potential for yKu(Yku80 and Yku70 )to mediate NHEJ. These results thus propose a solution to a long-standing conundrum, namely how to accommodate the apparently conflicting functions of Ku on telomeres. | 27930670 |
| 2015-08-01 12:02:00 | We found that the yku70-R456E mutant strain, which has markedly reduced association of Ku at telomeres, maintained WT levels of TLC1 nuclear localization. | 24879463 |
| Type | IDs |
|---|---|
| Synonymous | HDF1, NES24 |
| Gene |
UniProtKB-ID:
KU70_YEAST
UniprotKB:
P32807
UniParc:
UPI000004C4D7
EMBL:
D15052,
AM296303,
AM296302,
AM296297,
BK006946,
AM296298,
AM296301,
AY692863,
AM296294,
X70379,
AM296293,
AM296295,
AM296296,
AM296304,
AM296299,
AM296292,
Z49704
EnsemblGenome:
YMR284W
KO:
sce:YMR284W
|
| Nucleutide sequences |
EMBL-CDS:
CAL36019.1,
CAL36015.1,
BAA03648.1,
CAL36022.1,
CAL36021.1,
AAT92882.1,
CAL36013.1,
CAL36025.1,
CAA49840.1,
CAL36023.1,
CAL36018.1,
CAL36016.1,
CAL36014.1,
DAA10185.1,
CAL36020.1,
CAA89782.1,
CAL36024.1
Gene_ORFName:
YM8021.10
EnsemblGenome_TRS:
YMR284W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YMR284W
RefSeq:
NP_014011.1
|
| Others |
UniRef100:
UniRef100_P32807
UniRef90:
UniRef90_P32807
UniRef50:
UniRef50_P32807
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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