| Type | Description |
|---|---|
| Definition | ubiquitin-protein ligase RKR1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Cooperativity between the Ribosome-Associated Chaperone Ssb/RAC and the Ubiquitin Ligase Ltn1 in Ubiquitination of Nascent Polypeptides. | 32957466 |
| 2020-04-18 10:58:00 | Our findings suggest that carboxy-terminal alanine and threonine residues aggregation is detrimental, rather than adaptive, in cells with diminished Ltn1 function. | 31945107 |
| 2018-05-05 11:50:00 | The authors determined that the Rqc2p-mediated Carboxy-terminal Alanine and Threonine (CAT) tail elongation is mechanistically distinct from canonical translation, that Ltn1p-mediated ubiquitination depends on the poorly characterized Ribosome-associated Quality control Complex component Rqc1p, and that the process of CAT tailing enables robust ubiquitination of the nascent polypeptide. | 28718767 |
| 2016-12-17 10:08:00 | Data show that Saccharomyces cerevisiae proteins Rqc1, Ltn1, and Cdc48 prevent the aggregation of aberrant proteins that can only appear after C-terminal alanine-threonine tail (CAT-tail) addition by Rqc2. | 27129255 |
| 2016-04-09 11:30:00 | findings can explain the proteotoxicity of ribosome-stalled polypeptides and demonstrate the essential role of the in maintaining proteostasis | 26934223 |
| Type | IDs |
|---|---|
| Synonymous | LTN1 |
| Gene |
UniProtKB-ID:
LTN1_YEAST
UniprotKB:
Q04781
UniParc:
UPI000013B92C
EMBL:
Z48756,
BK006946,
Z48639
EnsemblGenome:
YMR247C
KO:
sce:YMR247C
|
| Nucleutide sequences |
EMBL-CDS:
CAA88574.1,
CAA88657.1,
DAA10148.1
Gene_ORFName:
YM9408.09C,
YM9920.01C
EnsemblGenome_TRS:
YMR247C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YMR247C
RefSeq:
NP_013975.1
|
| Others |
UniRef100:
UniRef100_Q04781
UniRef90:
UniRef90_Q04781
UniRef50:
UniRef50_Q04781
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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