| Type | Description |
|---|---|
| Definition | RNA-DNA hybrid ribonuclease |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 12:08:00 | Here we show that the translesion synthesis DNA polymerase eta (Pol eta) plays a role in DNA replication under low deoxyribonucleotides condition triggered by hydroxyurea. In particular, the catalytic reaction performed by Pol eta is detrimental for RNase H deficient cells, causing DNA damage checkpoint activation and G2/M arrest | 30847483 |
| 2019-07-20 12:29:00 | we observed a similar increase in repeat instability in RNase H-deficient cells when we either changed the direction of transcription-replication collisions, or flipped the repeat sequence such that the (UUC)n run occurred in the transcript. The increase in repeat expansions in RNase H-deficient strains was dependent on Rad52 and Pol32 proteins, suggesting that break-induced replication (BIR) is responsible for this effe | 29447396 |
| 2017-10-07 12:47:00 | Depleting endogenous RNase H activity impairs R-loop removal in Saccharomyces cerevisiae, causing DNA damage that occurs preferentially in the repetitive ribosomal DNA locus (rDNA). | 27938663 |
| 2016-08-27 11:45:00 | high-resolution mapping of mitotic recombination events throughout the yeast genome in diploid strains of Saccharomyces cerevisiae lacking RNase H1 (rnh1Delta), RNase H2 (rnh201Delta), or both RNase H1 and RNase H2 (rnh1Delta rnh201Delta) | 26400613 |
| 2010-01-21 00:00:00 | Data show that overexpression of a cellular RNase H, which degrades RNA in an RNA:DNA hybrid, completely suppressed the increase in Ty1 multimer formation in an rrm3 mutant. | 19414561 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RNH1_YEAST
UniprotKB:
Q04740
UniParc:
UPI00000531D3
EMBL:
Z49939,
BK006946,
X57160
EnsemblGenome:
YMR234W
KO:
sce:YMR234W
|
| Nucleutide sequences |
EMBL-CDS:
CAA90205.1,
CAA40448.1,
DAA10134.1
Gene_ORFName:
YM9959.16
EnsemblGenome_TRS:
YMR234W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YMR234W
RefSeq:
NP_013961.1
|
| Others |
UniRef100:
UniRef100_Q04740
UniRef90:
UniRef90_Q04740
UniRef50:
UniRef50_Q04740
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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