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855268 MTF1

855268

MTF1

RNA polymerase specificity factor

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition RNA polymerase specificity factor

研究结论

Date Results Publications
2021-02-06 13:51:00 Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial 33278362
2020-12-26 13:14:00 The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding. 32241911
2017-05-06 10:44:00 Rpo41-Mtf1 is an attractive candidate for serving as the primase to initiate lagging strand DNA synthesis during normal replication and/or to restart stalled replication from downstream ssDNA. 27311715
2016-05-28 12:20:00 The study examined a series of N-terminal deletion mutants of yeast mitochondrial RNA polymerase, Rpo41, and found that the N-terminal region does not abolish the effects of Mtf1; rather it contributes directly to enzyme catalysis. 26332125
2015-01-17 12:45:00 This study identifies the importance of the +1+2 AA promoter sequence interactions with Rpo41-Mtf1 in dictating pre-transcribing complex formation, which regulates the binding of initiating NTPs and the catalytic efficiency of transcription initiation. 25249624

名称对应

Type IDs
Gene
UniProtKB-ID: MTF1_YEAST
UniprotKB: P14908
UniParc: UPI00001683E2
EMBL: Z49939, BK006946, X13513
EnsemblGenome: YMR228W
KO: sce:YMR228W
Nucleutide sequences
EMBL-CDS: DAA10127.1, CAA31864.1, CAA90199.1
Gene_ORFName: YM9959.10
EnsemblGenome_TRS: YMR228W_mRNA
Protein sequencees
EnsemblGenome_PRO: YMR228W
RefSeq: NP_013955.1
Others
UniRef100: UniRef100_P14908
UniRef90: UniRef90_P14908
UniRef50: UniRef50_P14908

全选

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研究热度

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