| Type | Description |
|---|---|
| Definition | ATP-dependent DNA helicase YKU80 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:29:00 | CDK-mediated Yku80 Phosphorylation Regulates the Balance Between Non-homologous End Joining (NHEJ) and Homologous Directed Recombination (HDR). | 33217428 |
| 2019-06-01 12:28:00 | DNA with ends occluded by the DNA end-joining factor Ku70-Ku80 becomes a suitable substrate for long-range 5'-3' resection when a nick is introduced at a locale proximal to one of the Ku-bound DNA ends. | 30224356 |
| 2017-05-13 14:52:00 | the yKu-distal portion of telomeres is bound by Rap1, which in turn reduces the potential for yKu(Yku80 and Yku70 )to mediate NHEJ. These results thus propose a solution to a long-standing conundrum, namely how to accommodate the apparently conflicting functions of Ku on telomeres. | 27930670 |
| 2016-05-21 13:16:00 | The authors show that Sir4 - a previously identified Ku-binding protein that is a component of telomeric silent chromatin - is required for Ku-mediated telomere lengthening and telomerase recruitment. | 26218225 |
| 2015-08-01 12:02:00 | Deletion of Est1 has a much greater impact on telomere lengthening in the presence of a Cdc13-Est2 fusion than deletion of YKU80, suggesting that any contribution that Ku may have in telomerase activation is minor compared to that of Est1. | 24879463 |
| Type | IDs |
|---|---|
| Synonymous | HDF2 |
| Gene |
UniProtKB-ID:
KU80_YEAST
UniprotKB:
Q04437
UniParc:
UPI0000034135
EMBL:
AM296336,
Z49702,
AM296341,
AM296344,
AM296335,
AM296345,
AM296340,
AM296342,
AM296334,
AM296343,
AM296333,
AM296339,
AM296337,
AM296338,
BK006946
EnsemblGenome:
YMR106C
KO:
sce:YMR106C
|
| Nucleutide sequences |
EMBL-CDS:
CAL35978.1,
CAA89742.1,
CAL35979.1,
DAA10003.1,
CAL35976.1,
CAL35974.1,
CAL35982.1,
CAL35977.1,
CAL35981.1,
CAL35972.1,
CAL35984.1,
CAL35983.1,
CAL35973.1,
CAL35975.1,
CAL35980.1
Gene_ORFName:
YM9718.05C
EnsemblGenome_TRS:
YMR106C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YMR106C
RefSeq:
NP_013824.1
|
| Others |
UniRef100:
UniRef100_Q04437
UniRef90:
UniRef90_Q04437
UniRef50:
UniRef50_Q04437
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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