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855013 CDC5

855013

CDC5

polo kinase CDC5

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition polo kinase CDC5

研究结论

Date Results Publications
2020-09-26 13:09:00 Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA. 32810142
2019-03-16 11:12:00 we confirmed that this release indeed accompanies the dissociation of acetylated Smc3 as well as Rec8 from meiotic chromosomes during late prophase-I. This release requires, in addition to PLK, the cohesin regulator, Wapl (Rad61/Wpl1 in yeast), and Dbf4-dependent Cdc7 kinase (DDK) 30605471
2017-08-12 10:06:00 Cdc5 interacts with cohesin in vivo, and cohesin is required for association of Cdc5 at centromeric chromatin. Cohesin removal from centromeric chromatin requires Cdc5 but removal at distal chromosomal arm sites does not. Results define a novel role for Cdc5 in regulating removal of centromeric cohesins and faithful chromosome segregation. 27226485
2017-05-06 10:59:00 budding yeast Plk1, Cdc5, is pre-deposited onto cohesin engaged in cohesion on chromosome arms in G2/M phase cells. The Cdc5-cohesin association is mediated by direct interaction between the polo-box domain of Cdc5 and Scc1 phosphorylated at multiple sites in its middle region. 27325700
2016-12-17 12:02:00 Polo kinase Cdc5 mediates centrosome-dependent bypass of the DNA damage checkpoint. 26832404

名称对应

Type IDs
Synonymous MSD2, PKX2
Gene
UniProtKB-ID: CDC5_YEAST
UniprotKB: P32562
UniParc: UPI0000127258
EMBL: Z48613, M84220, BK006946
EnsemblGenome: YMR001C
KO: sce:YMR001C
Nucleutide sequences
EMBL-CDS: DAA09899.1, CAA88516.1, AAA02576.1
Gene_ORFName: YM8270.03C
EnsemblGenome_TRS: YMR001C_mRNA
Protein sequencees
EnsemblGenome_PRO: YMR001C
RefSeq: NP_013714.1
Others
UniRef100: UniRef100_P32562
UniRef90: UniRef90_P32562
UniRef50: UniRef50_P32562

全选

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研究热度

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