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855012 YPT7

855012

YPT7

Rab family GTPase YPT7

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Rab family GTPase YPT7

研究结论

Date Results Publications
2019-10-12 10:59:00 In this study, we demonstrate that activated Ypt7p localizes to the vacuolar membrane in cells lacking all yeast Rab5 genes. We also show that the vps21Delta ypt7Delta double mutant exhibits a much severer vacuolar phenotype in comparison with the vps21Delta or ypt7Delta single mutant. 30682048
2016-06-04 10:14:00 Homotypic fusion and protein-sorting/class C vacuole protein-sorting (HOPS/class C Vps) complex can tether low-curvature membranes, that is, liposomes with a diameter of 100 nm, only when the yeast vacuolar Ypt7p is present in both tethered membranes. 25995379
2014-11-08 13:45:00 Guanine nucleotide exchange factor activity of the Mon1-Ccz1 complex towards Ypt7 requires the interface formed by their longin domains. 24413168
2013-02-23 10:02:00 phosphorylation of vacuole protein sorting complex (HOPS) by recombinant Yck3p confers strict requirement for GTP-bound Ypt7p for binding phosphorylated HOPS, for optimal membrane tethering and proteoliposome fusion; guanine nucleotide specificity of the vacuolar fusion Rab Ypt7p is conferred through downstream posttranslational modification of its effector complex 22787280
2012-11-17 11:32:00 yeast retromer trimer antagonizes Ypt7-regulated organelle tethering and fusion of endosomes/vacuoles via recognition of Ypt7 22593205

名称对应

Type IDs
Synonymous AST4, VAM4
Gene
UniProtKB-ID: YPT7_YEAST
UniprotKB: P32939
UniParc: UPI0000053062
EMBL: Z48613, X68144, BK006946, D64114
EnsemblGenome: YML001W
KO: sce:YML001W
Nucleutide sequences
EMBL-CDS: BAA10973.1, CAA48244.1, CAA88515.1, DAA09898.1
Gene_ORFName: YM8270.02
EnsemblGenome_TRS: YML001W_mRNA
Protein sequencees
EnsemblGenome_PRO: YML001W
RefSeq: NP_013713.1
Others
UniRef100: UniRef100_P32939
UniRef90: UniRef90_P32939
UniRef50: UniRef50_P32939

全选

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研究热度

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