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854976 RAD52

854976

RAD52

recombinase RAD52

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition recombinase RAD52

研究结论

Date Results Publications
2021-02-27 13:49:00 Emerging non-canonical roles for the Rad51-Rad52 interaction in response to double-strand breaks in yeast. 32399607
2020-05-23 10:53:00 Cooperation between Rad52 liquid droplets and various types of nuclear filaments promotes the assembly and function of the DNA repair centre. 32019927
2020-05-16 11:55:00 In S. cerevisiae telomere addition is significantly reduced in the absence of the Rad51 recombinase, while loss of Rad52, required for Rad51 nucleoprotein filament formation, has no effect. Deletion of RAD52 suppresses the defect of the rad51Delta strain, suggesting that Rad52 inhibits de novo telomere addition in the absence of Rad51. 32012161
2020-02-22 10:59:00 Rad52 competes with Sgs1 for DNA end binding and inhibits Sgs1 translocation along DNA, identifying a role for Rad52 in limiting ssDNA generated by end resection. 31542296
2019-07-20 12:29:00 we observed a similar increase in repeat instability in RNase H-deficient cells when we either changed the direction of transcription-replication collisions, or flipped the repeat sequence such that the (UUC)n run occurred in the transcript. The increase in repeat expansions in RNase H-deficient strains was dependent on Rad52 and Pol32 proteins, suggesting that break-induced replication (BIR) is responsible for this effe 29447396

名称对应

Type IDs
Gene
UniProtKB-ID: RAD52_YEAST
UniprotKB: P06778
UniParc: UPI0000D89849, UPI00001683C2, UPI0000D8984A
EMBL: AY693144, M10249, BK006946, Z46659
EnsemblGenome: YML032C
KO: sce:YML032C
Nucleutide sequences
EMBL-CDS: DAA09866.1, CAA86623.1, AAT93163.1, AAA50352.1
EnsemblGenome_TRS: YML032C_mRNA
Protein sequencees
EnsemblGenome_PRO: YML032C
RefSeq: NP_013680.2
Others
UniRef100: UniRef100_P06778
UniRef90: UniRef90_P06778
UniRef50: UniRef50_P06778

全选

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研究热度

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