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854937 ORC1

854937

ORC1

origin recognition complex subunit 1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition origin recognition complex subunit 1

研究结论

Date Results Publications
2020-09-05 13:58:00 Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase. 32569318
2019-09-28 10:22:00 Direct interactions with nucleosomes are essential for Orc1 to maintain the integrity of rDNA borders during meiosis. 31263106
2018-01-06 12:01:00 the diminished cell-cycle changes in nucleosome occupancy around origins in the orc1-161 mutant are associated with an abnormal global origin usage profile, suggesting that proper establishment of nucleosome occupancy around origins is a critical step for regulation of global origin activities. Our work thus establishes nucleosome occupancy as a novel and key chromatin parameter for proper origin regulation. 27895110
2016-08-27 10:52:00 Specific ORC1 to DNA replication origins depends on highly conserved basic residues. 26456755
2013-08-31 11:11:00 Data indicate that Cdt1-MCM2-7 complex activates ORC/Cdc6 ATP-hydrolysis to promote helicase loading. 23603117

名称对应

Type IDs
Gene
UniProtKB-ID: ORC1_YEAST
UniprotKB: P54784
UniParc: UPI00000531B0
EMBL: Z38114, U34860, BK006946
EnsemblGenome: YML065W
KO: sce:YML065W
Nucleutide sequences
EMBL-CDS: CAA86256.1, DAA09832.1, AAB38248.1
EnsemblGenome_TRS: YML065W_mRNA
Protein sequencees
EnsemblGenome_PRO: YML065W
RefSeq: NP_013646.1
Others
UniRef100: UniRef100_P54784
UniRef90: UniRef90_P54784
UniRef50: UniRef50_P54784

全选

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研究热度

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