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854790 TIM44

854790

TIM44

protein translocase subunit TIM44

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition protein translocase subunit TIM44

研究结论

Date Results Publications
2018-02-10 10:10:00 Using site-specific in vivo crosslinking and genetic approaches in Saccharomyces cerevisiae, the authors found that both domains of Tim44 interact with the major matrix-exposed loop of Tim23, with the C-terminal domain (CTD) binding Tim17 as well. 28440746
2016-10-08 10:23:00 These data suggest that the translocation channel and the import motor of the TIM23 complex communicate through rearrangements of the two domains of Tim44 that are stimulated by translocating proteins. 26714107
2015-02-07 11:14:00 Tim23 mitochondrial motor components are tethered to translocon via the scaffold Tim44, with regulatory protein Pam17 having independent interaction site. 25157107
2010-01-21 13:13:00 Genetic and biochemical analyses reveal synthetic interactions between PAM17 and TIM44. 19577659
2010-01-21 00:00:00 interactions between Tim44 and mtHsp70, controlled by polypeptide binding, are required for efficient translocation across the mitochondrial inner membrane 15489862

名称对应

Type IDs
Synonymous ISP45, MIM44, MPI1
Gene
UniProtKB-ID: TIM44_YEAST
UniprotKB: Q01852
UniParc: UPI000012D5E5
EMBL: BK006942, Z46881, X67276
EnsemblGenome: YIL022W
KO: sce:YIL022W
Nucleutide sequences
EMBL-CDS: CAA86970.1, DAA08523.1, CAA47693.1
EnsemblGenome_TRS: YIL022W_mRNA
Protein sequencees
EnsemblGenome_PRO: YIL022W
RefSeq: NP_012242.1
Others
UniRef100: UniRef100_Q01852
UniRef90: UniRef90_Q01852
UniRef50: UniRef50_Q01852

全选

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