| Type | Description |
|---|---|
| Definition | Irr1p |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 11:32:00 | We demonstrate that this conserved domain is required for DNA binding by Scc3-Scc1 in vitro, as well as for the enrichment of cohesin on chromosomes and for cell viability. These findings suggest that the Scc3-Scc1 DNA-binding interface plays a central role in the recruitment of cohesin complexes to chromosomes and therefore for cohesin to faithfully execute its functions during cell division. | 30109982 |
| 2015-12-26 10:52:00 | We show that residues Y371 and K372 within the SCD are critical for viability and chromosome condensation but dispensable for cohesion. However, scc3 Y371A and scc3 K372A bind normally to Mcd1 | 25748820 |
| 2014-11-22 10:05:00 | Scc3 C-terminal domain binds Scc1 and promotes de-acetylation of Smc3 upon Scc1 cleavage. | 25171859 |
| 2013-10-26 10:59:00 | expression of 33 genes is affected by the presence of the mutated Irr1-1p and identify those genes. This supports the suggested role of Irr1p in the regulation of transcription. Irr1p may interact with elements of transcriptional coactivator Mediator | 23730682 |
| 2011-08-20 10:09:00 | The expression of MCD1 was not subject to Scc3 regulation in vegetative cells. Scc3 and Smc1 are both required for the production of the meiosis-specific subunit Rec8. | 21270391 |
| Type | IDs |
|---|---|
| Synonymous | SCC3 |
| Gene |
UniProtKB-ID:
SCC3_YEAST
UniprotKB:
P40541
UniParc:
UPI00000530AE
EMBL:
Z46881,
U17918,
BK006942
EnsemblGenome:
YIL026C
KO:
sce:YIL026C
|
| Nucleutide sequences |
EMBL-CDS:
DAA08520.1,
CAA86966.1,
AAC49039.1
EnsemblGenome_TRS:
YIL026C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YIL026C
RefSeq:
NP_012238.1
|
| Others |
UniRef100:
UniRef100_P40541
UniRef90:
UniRef90_P40541
UniRef50:
UniRef50_P40541
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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