| Type | Description |
|---|---|
| Definition | scinderin |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 11:14:00 | down-regulation of SCIN expression may relate with the progression of chronic myeloid leukemia | 31204912 |
| 2019-03-02 12:21:00 | Findings indicate that decreased scinderin (SCIN) expression associated with its promoter methylation is a valuable biomarker for predicting adverse prognosis in acute myeloid leukemia (AML) patients. | 29457658 |
| 2017-06-24 10:12:00 | Data suggest that scinderin (Scin) played a vital role in the development of developmental dysplasia of the hip (DDH). | 28213129 |
| 2017-05-06 18:10:00 | Epistasis analysis identified a statistically significant interaction between CDC42 and SCIN SNPs which are strongly associated with CDC42 and SCIN gene expression levels and map to regulatory elements in skin cells. This interaction has important biological relevance since CDC42 and SCIN proteins have opposite effects in actin cytoskeleton organization and dynamics, which underlies melanoma cell migration and invasion. | 27347659 |
| 2017-02-18 10:49:00 | High levels of SCIN expression in gastric cancer tissue correlate with poor prognosis of patients. SCIN enhances the invasion and metastasis of GC cells through activating the Cdc42 pathway to increase the formation of filopodia. | 27033455 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ADSV_HUMAN
UniprotKB:
Q9Y6U3
UniParc:
UPI000013C4DF,
UPI000015F543,
UPI000036FD3C
EMBL:
AF276507,
AK075123,
BC021090,
AK290363,
BU193785,
AK027778,
AB067492,
CH471073,
AC005281
Ensembl:
ENSG00000006747
KO:
hsa:85477
|
| Nucleutide sequences |
EMBL-CDS:
BAB67798.1,
BAB55361.1,
EAW93647.1,
AAD15423.1,
BAC11416.1,
AAH21090.1,
AAK60494.1,
BAF83052.1
Ensembl_TRS:
ENST00000297029,
ENST00000519209,
ENST00000341757
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000297029,
ENSP00000430997,
ENSP00000341375
RefSeq:
NP_149119.1,
NP_001106177.1,
XP_024302748.1
|
| Others |
UniRef100:
UniRef100_Q9Y6U3
UniRef90:
UniRef90_Q9Y6U3
UniRef50:
UniRef50_Q9Y6U3
UniGene:
Hs.633359,
Hs.655515
CCDS:
CCDS47545.1,
CCDS47546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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