| Type | Description |
|---|---|
| Definition | ubiquitin-binding SDF ubiquitin ligase complex subunit MET30 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:11:00 | Cdc48 cofactor Shp1 regulates signal-induced SCF(Met30) disassembly. | 32817489 |
| 2020-05-16 11:44:00 | Study revealed that two essential Skp, Cullin, F-box (SCF) ubiquitin ligases defined by the F-box proteins Met30 and Cdc4 cooperatively regulate Cse4 (S. cerevisiae homolog of human centromere protein-A (CENP-A)) proteolysis under normal physiological conditions. Results suggest SCF-Met30/Cdc4-mediated proteolysis of Cse4 is one of the major mechanisms that prevents stable maintenance of Cse4 at non-centromeric regions. | 32032354 |
| 2016-06-04 11:29:00 | This ubiquitylation and degradation pathway acts on Met30 that is dissociated from Skp1. Unexpectedly, this pathway required the cullin component Cdc53/Cul1 but was independent of the other central SCF component Skp1 | 26656496 |
| 2015-01-17 12:24:00 | In Saccharomyces cerevisiae, transcription of the MET regulon is controlled by ubiquitination of the transcription factor Met4, which is carried out by the SCF(Met30) E3 ubiquitin ligase. | 24648496 |
| 2011-01-29 11:05:00 | The stability of these DNA-binding cofactors is regulated by SCF(Met30). | 21172660 |
| Type | IDs |
|---|---|
| Synonymous | ZRG11 |
| Gene |
UniProtKB-ID:
MET30_YEAST
UniprotKB:
P39014
UniParc:
UPI000012F726
EMBL:
Z46861,
BK006942,
L26505
EnsemblGenome:
YIL046W
KO:
sce:YIL046W
|
| Nucleutide sequences |
EMBL-CDS:
AAA96717.1,
DAA08502.1,
CAA86905.1
EnsemblGenome_TRS:
YIL046W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YIL046W
RefSeq:
NP_012218.1
|
| Others |
UniRef100:
UniRef100_P39014
UniRef90:
UniRef90_P39014
UniRef50:
UniRef50_P39014
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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