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85476 GFM1

85476

GFM1

G elongation factor mitochondrial 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition G elongation factor mitochondrial 1

研究结论

Date Results Publications
2021-04-13 10:15:00 Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1. 32602580
2020-11-28 13:17:00 [Analysis of GFM1 gene mutations in a family with combined oxidative phosphorylation deficiency 1]. 33210482
2020-09-12 16:03:00 Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. 32737313
2018-02-10 10:09:00 Functional studies demonstrated decreased GFM1 protein levels, suggested disrupted assembly of mitochondrial complexes III and V and decreased activities of mitochondrial complexes I and IV, all indicating combined OXPHOS deficiency. 28216230
2017-01-14 10:12:00 In the present study, a nanoparticle modified with EGFP-EGF1 (ENP) was constructed as a multitargeting drug delivery system. The protein binding experiment showed EGFP-EGF1 could bind well to A549 tumor cells and other stromal cells including neo-vascular cells, tumor-associated fibroblasts, and tumor-associated macrophages 26890991

名称对应

Type IDs
Synonymous COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1, mtEF-G1
Gene
UniProtKB-ID: EFGM_HUMAN, C9IZ01_HUMAN, E5KND5_HUMAN
UniprotKB: Q96RP9, C9IZ01, E5KND5
UniParc: UPI0000E5AA5A, UPI0001B78F61, UPI000006232D
EMBL: HQ205237, AF309777, HQ205229, AC025033, KU178816, HQ205248, HQ205255, HQ205261, HQ205251, HQ205230, HQ205234, HQ205263, HQ205240, HQ205247, BC049210, HQ205238, HQ205249, AC080013, HQ205264, HQ205231, HQ205262, HQ205252, HQ205245, AK092293, HQ205258, HQ205226, HQ205265, HQ205243, HQ205227, CH471052, HQ205241, AK315031, AF367998, HQ205244
Ensembl: ENSG00000168827
KO: hsa:85476
Nucleutide sequences
EMBL-CDS: AAK53402.1, AAK58877.1, AAH49210.1, EAW78682.1, EAW78677.1, BAG37516.1, BAG52523.1, ADP90713.1, ADP90730.1, ADP90715.1, ADP90699.1, ADP90720.1, ADP90706.1, ADP90723.1, ADP90717.1, ALQ34274.1, ADP90698.1, ADP90716.1, ADP90694.1, ADP90726.1, ADP90731.1, ADP90702.1, ADP90733.1, ADP90697.1, ADP90705.1, ADP90695.1, ADP90712.1, ADP90709.1, ADP90729.1, ADP90719.1, ADP90711.1, ADP90732.1, ADP90708.1
Ensembl_TRS: ENST00000486715, ENST00000264263, ENST00000478576
Protein sequencees
Ensembl_PRO: ENSP00000419038, ENSP00000264263, ENSP00000418755
RefSeq: NP_001361286.1, NP_001361285.1, NP_001361288.1, NP_001295095.1, NP_001361289.1, NP_079272.4, NP_001361287.1, NP_001295093.1, NP_001361290.1, NP_001361284.1
Others
UniRef100: UniRef100_Q96RP9, UniRef100_C9IZ01
UniRef90: UniRef90_Q96RP9, UniRef90_C9IZ01
UniRef50: UniRef50_H2ZAD0, UniRef50_Q96RP9
UniGene: Hs.518355
CCDS: CCDS77851.1, CCDS33885.1

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