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854738 HOP1

854738

HOP1

Hop1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Hop1p

研究结论

Date Results Publications
2019-07-13 11:34:00 Data show that Hop1 protein possesses conformational dynamics similar to spindle checkpoint protein MAD2 (Mad2), and identify closure motifs in the Hop1 binding partner Red1 protein. 29186573
2019-01-19 10:09:00 crystal structures of the Mek1 FHA domain in the apo state and in complex with the Hop1 pT318 peptide are presented, demonstrating that the hydrophobic residues Phe320 and Val321 at the pT+2 and pT+3 positions in the ligand contribute to the preferential recognition. 30289413
2018-07-21 11:50:00 These localization patterns closely tracked the distribution of Red1 and Hop1, axis proteins required for Mek1 activation. These findings provide insight into the spatial disposition of Mek1 kinase activity and the higher order organization of recombining meiotic chromosomes 28986445
2016-05-07 11:33:00 Hop1 phospho-T318 and phospho-S298 constitute key components of the Tel1/Mec1- based meiotic recombination surveillance (MRS) network and facilitate coupling of meiotic recombination and progression during both unperturbed and challenged meiosis 26225562
2014-11-08 13:38:00 Pch2 prevents Mec1/Tel1-mediated Hop1 phosphorylation occurring independently of Red1 in Saccharomyces cerevisiae meiosis. 24465650

名称对应

Type IDs
Gene
UniProtKB-ID: HOP1_YEAST
UniprotKB: P20050
UniParc: UPI000012CAD4
EMBL: Z38060, J04877, BK006942, Z37997
EnsemblGenome: YIL072W
KO: sce:YIL072W
Nucleutide sequences
EMBL-CDS: CAA86151.1, CAA86098.1, AAA34682.1, DAA08478.1
EnsemblGenome_TRS: YIL072W_mRNA
Protein sequencees
EnsemblGenome_PRO: YIL072W
RefSeq: NP_012193.3
Others
UniRef100: UniRef100_P20050
UniRef90: UniRef90_P20050
UniRef50: UniRef50_P20050

全选

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研究热度

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