| Type | Description |
|---|---|
| Definition | RSC chromatin remodeling complex ATPase subunit STH1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:52:00 | The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex. | 31711754 |
| 2020-05-16 12:38:00 | The wild-type bromodomain preferentially recognizes H3K14ac and H4K20ac peptides. Mutagenesis studies-guided by the crystal structure revealed loop residues Ser1276 and Trp1338 as key determinants for such interactions. Strikingly, point mutations of each of these residues substantially increased peptide binding affinity and selectivity, respectively. | 31327661 |
| 2017-08-05 12:37:00 | Sliding-to-ejection involves a continuum of DNA translocation efficiency, consistent with higher magnitudes of ATPase and coupling activities (involving and Sth1 domains), enabling the simultaneous rupture of multiple histone-DNA contacts facilitating ejection. | 27153540 |
| 2014-11-22 13:02:00 | Results show that depletion of STH1, the ATPase subunit of RSC, causes enhanced sensitivity to the DNA alkylating agent methyl methanesulfonate (MMS). | 24674626 |
| 2010-01-21 00:00:00 | results suggest that Nps1p/RSC plays important roles during the spore development process by controlling gene expression for initiating both meiosis and spore morphogenesis, and ensures proper expression timing of late meiotic genes | 15118322 |
| Type | IDs |
|---|---|
| Synonymous | NPS1 |
| Gene |
UniProtKB-ID:
STH1_YEAST
UniprotKB:
P32597
UniParc:
UPI0000053006
EMBL:
BK006942,
D10595,
Z46833,
M83755,
DQ115392
EnsemblGenome:
YIL126W
KO:
sce:YIL126W
|
| Nucleutide sequences |
EMBL-CDS:
AAA35120.1,
BAA01446.1,
CAA86866.1,
DAA08427.1,
AAZ22501.1
EnsemblGenome_TRS:
YIL126W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YIL126W
RefSeq:
NP_012140.1
|
| Others |
UniRef100:
UniRef100_P32597
UniRef90:
UniRef90_P32597
UniRef50:
UniRef50_P32597
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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