| Type | Description |
|---|---|
| Definition | kinetochore-associated Ndc80 complex subunit NDC80 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:21:00 | Our results suggest the stoichiometry of outer kinetochore submodules is strongly influenced by factors at the kinetochore-microtubule interface such as Fin1 and Dam1, and phosphorylation by cyclin-dependent kinase. | 31118239 |
| 2020-02-22 11:28:00 | The authors suggest that prior to its assembly at the kinetochore, the Ndc80 complex interchanges between bent (auto-inhibited) and open conformations. Once assembled, its association with MIND stabilizes the Ndc80 complex in a straightened form for higher affinity microtubule binding. | 31045495 |
| 2019-02-02 10:10:00 | We used this assay to investigate why kinetochores recruit the microtubule-binding Ndc80 complex via two receptors: the Mis12 complex and CENP-T. Although the CENP-T pathway is non-essential in yeast, we demonstrate that it becomes essential for viability and Ndc80c recruitment when the Mis12 pathway is crippled by defects in Dsn1 phosphorylation | 30117803 |
| 2018-06-09 11:52:00 | The authors discovered that in budding yeast, kinetochore inactivation during meiosis occurs by reducing the abundance of a limiting subunit, Ndc80. | 28906249 |
| 2018-06-09 11:52:00 | Thus, expression of a 5' extended mRNA isoform causes transcriptional interference at the downstream promoter of NDC80. The authors demonstrate that this is an effective mechanism to promote dynamic changes in gene expression during cell differentiation. | 28906248 |
| Type | IDs |
|---|---|
| Synonymous | HEC1, TID3 |
| Gene |
UniProtKB-ID:
NDC80_YEAST
UniprotKB:
P40460
UniParc:
UPI000013B451
EMBL:
Z38059,
BK006942
EnsemblGenome:
YIL144W
KO:
sce:YIL144W
|
| Nucleutide sequences |
EMBL-CDS:
CAA86134.1,
DAA08409.1
EnsemblGenome_TRS:
YIL144W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YIL144W
RefSeq:
NP_012122.3
|
| Others |
UniRef100:
UniRef100_P40460
UniRef90:
UniRef90_P40460
UniRef50:
UniRef50_P40460
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员