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854656 MCM10

854656

MCM10

Mcm10p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Mcm10p

研究结论

Date Results Publications
2019-03-16 12:15:00 potent DNA strand-annealing protein that inhibits fork regression by SMARCAL1 30598452
2018-06-09 11:02:00 This report demonstrates that Mcm10, an essential replication protein unique to eukaryotes, binds the replicative helicase CMG and greatly stimulates its helicase activity in vitro. Most significantly, Mcm10 enables CMG and the replisome to bypass blocks on the non-tracking DNA strand. 28869037
2017-10-21 11:49:00 An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-alpha to Mcm2-7. 28510759
2017-07-01 11:53:00 These data suggest that DNA binding by Mcm10 is essential for the initiation of DNA replication. 27751725
2016-08-13 11:10:00 Mcm10 directly binds the Minichromosome Maintenance Complex via Mcm2 and the Mcm6 C terminus. 26719337

名称对应

Type IDs
Synonymous DNA43
Gene
UniProtKB-ID: MCM10_YEAST
UniprotKB: P32354
UniParc: UPI0000036C5F
EMBL: BK006942, Z38059, M83540
EnsemblGenome: YIL150C
KO: sce:YIL150C
Nucleutide sequences
EMBL-CDS: AAA34574.1, DAA08403.1, CAA86128.1
EnsemblGenome_TRS: YIL150C_mRNA
Protein sequencees
EnsemblGenome_PRO: YIL150C
RefSeq: NP_012116.1
Others
UniRef100: UniRef100_P32354
UniRef90: UniRef90_P32354
UniRef50: UniRef50_P32354

全选

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研究热度

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