| Type | Description |
|---|---|
| Definition | slingshot protein phosphatase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:13:00 | the N-terminal region of human Slingshot2 auto-inhibits its phosphatase activity in a noncompetitive manner | 30154244 |
| 2015-10-31 10:53:00 | Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified. | 25568344 |
| 2014-04-26 12:26:00 | data indicate that: (a) apoptotic cell death in FLCN-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD syndrome related tumors | 23416984 |
| 2010-06-30 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20477815 |
| 2010-01-21 00:00:00 | Expression of phosphatase-dead versions of SSH proteins, SSH1, SSH2 & SSH3 results in phosphorylation/inactivation of cofilin, changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes. | 17848544 |
| Type | IDs |
|---|---|
| Synonymous | SSH-2, SSH-2L |
| Gene |
UniProtKB-ID:
SSH2_HUMAN,
B4DK64_HUMAN,
A0A3B3ITS1_HUMAN,
F5H527_HUMAN
UniprotKB:
Q76I76,
B4DK64,
A0A3B3ITS1,
F5H527
UniParc:
UPI00005E2744,
UPI00005E2743,
UPI0002065A97,
UPI000006EACD,
UPI00017A71EA,
UPI000006EAE3,
UPI00001D6272
EMBL:
AC104564,
AC104982,
BC011636,
AK296413,
AF484838,
AB051512,
AB099290,
AB072359,
BC008941,
BC068223,
CH471159,
AB072358,
AC023389,
AC087510
Ensembl:
ENSG00000141298
KO:
hsa:85464
|
| Nucleutide sequences |
EMBL-CDS:
AAH11636.2,
BAC97813.1,
AAL92027.1,
BAB84118.1,
AAH68223.1,
BAB21816.1,
AAH08941.1,
BAB84117.1,
BAG59076.1,
EAW51209.1
Gene_ORFName:
hCG_2003225
Ensembl_TRS:
ENST00000269033,
ENST00000324677,
ENST00000540801
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000269033,
ENSP00000497894,
ENSP00000444743
RefSeq:
XP_005258115.1,
NP_203747.2,
XP_016880741.1,
NP_001269058.1,
XP_011523704.1,
XP_005258117.1,
XP_016880744.1,
XP_011523709.1,
NP_001269059.1,
XP_005258116.1,
XP_016880742.1,
XP_016880740.1,
XP_016880743.1,
XP_011523707.1,
NP_001269060.1,
XP_011523706.1,
XP_006722212.1,
XP_011523708.1
|
| Others |
UniRef100:
UniRef100_A0A3B3ITS1,
UniRef100_B4DK64,
UniRef100_Q76I76,
UniRef100_F5H527
UniRef90:
UniRef90_Q76I76,
UniRef90_Q76I76-2
UniRef50:
UniRef50_Q76I76,
UniRef50_Q76I76-2
UniGene:
Hs.654754
CCDS:
CCDS11253.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Toronto |
3 |
| 2 |
University of Cambridge |
2 |
| 3 |
National Cancer Institute |
2 |
| 4 |
University of Oxford |
2 |
| 5 |
Lunenfeld-Tanenbaum Research Institute |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Sumio Sugano |
3 |
| 2 |
Yutaka Suzuki |
3 |
| 3 |
Kensaku Mizuno |
3 |
| 4 |
Matthias Mann |
2 |
| 5 |
Keiichi Nagai |
2 |