| Type | Description |
|---|---|
| Definition | tankyrase 1 binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | TCF3-activated FAM201A enhances cell proliferation and invasion via miR-186-5p/TNKS1BP1 axis in triple-negative breast cancer. | 33011533 |
| 2017-11-18 10:28:00 | Results found that TNKS1BP1 was upregulated in human lung adenocarcinoma tissues, and regulates genome stability, mainly through affecting the homologous recombination pathway of DNA double-strand breaks. These results indicate that overexpression of TNKS1BP1 might affect the outcomes of lung cancer patients to chemotherapy and radiotherapy. | 28058814 |
| 2017-09-16 12:33:00 | In clinical samples of pancreatic cancer, TNKS1BP1 expression was reduced in invasive regions. We propose that the tankyrase-TNKS1BP1 axis constitutes a posttranslational modulator of cell invasion whose aberration promotes cancer malignancy | 28202517 |
| 2016-01-16 10:09:00 | TNKS1BP1 has a role in DNA double-strand break repair though DNA-PKcs autophosphorylation which is dependent on | 25749521 |
| 2010-01-21 00:00:00 | We also demonstrate a requirement for tankyrase-1 in the assembly of bipolar spindles, and identify the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. | 16244666 |
| Type | IDs |
|---|---|
| Synonymous | TAB182 |
| Gene |
UniProtKB-ID:
TB182_HUMAN,
A0A024R542_HUMAN
UniprotKB:
Q9C0C2,
A0A024R542
UniParc:
UPI00001C0A5C,
UPI000013DB72
EMBL:
BC023622,
CH471076,
BC150333,
AB051528,
AK074113,
AF441771,
AK124903,
HM005619,
AP000781
Ensembl:
ENSG00000149115
KO:
hsa:85456
|
| Nucleutide sequences |
EMBL-CDS:
EAW73731.1,
AAM15531.1,
BAB21832.2,
AAI50334.1,
BAB84939.1,
AAH23622.1,
BAC85989.1,
AEE61216.1,
EAW73732.1,
EAW73733.1
Gene_ORFName:
hCG_1811635
Ensembl_TRS:
ENST00000532437,
ENST00000358252
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350990,
ENSP00000437271
RefSeq:
XP_006718788.1,
XP_011543627.1,
NP_203754.2
|
| Others |
UniRef100:
UniRef100_Q9C0C2
UniRef90:
UniRef90_Q9C0C2
UniRef50:
UniRef50_Q9C0C2
UniGene:
Hs.530730
CCDS:
CCDS7951.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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