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854508 MIP1

854508

MIP1

DNA-directed DNA polymerase gamma MIP1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DNA-directed DNA polymerase gamma MIP1

研究结论

Date Results Publications
2020-05-09 12:18:00 N-terminal deletions in Mip1 polymerases abolish polymerization and decrease exonucleolytic degradation, whereas moderate C-terminal deletions reduce polymerization. Similarly, to the N-terminal deletions, an extended C-terminal deletion of 298 amino acids is deficient in nucleotide addition and exonucleolytic degradation of double and single-stranded DNA. 31445096
2017-04-20 16:27:00 Yeast Mip1, the mitochondrial DNA polymerase gamma, harbors a conserved C-terminal extension required for maintenance of mitochondrial DNA in vivo. 16491467
2016-06-04 11:53:00 Herein the authors found that Rpo41 transcribes RNAs that can be extended by Mip1 on single and double-stranded DNA. 26184436
2015-10-31 10:04:00 Our study also further confirms the utility of yeast Mip1p as a tool for studying human DNA polymerase (pol gamma)variants. 26077851
2015-07-04 15:24:00 Disrupting exonuclease activity of mutant variants was not associated with increased spontaneous mutagenesis compared with exonuclease-proficient alleles, suggesting that most or all of the mtDNA was replicated by wild type Mip1. 25340760

名称对应

Type IDs
Gene
UniProtKB-ID: DPOG_YEAST
UniprotKB: P15801
UniParc: UPI00001297CD
EMBL: J05117, BK006948, Z75238, Z49821, U42227
EnsemblGenome: YOR330C
KO: sce:YOR330C
Nucleutide sequences
EMBL-CDS: AAA85442.1, CAA99652.1, CAA89977.1, DAA11093.1, AAA17543.1
EnsemblGenome_TRS: YOR330C_mRNA
Protein sequencees
EnsemblGenome_PRO: YOR330C
RefSeq: NP_014975.2
Others
UniRef100: UniRef100_P15801
UniRef90: UniRef90_P15801
UniRef50: UniRef50_P15801

全选

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研究热度

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