| Type | Description |
|---|---|
| Definition | protein-transporting protein SEC63 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62. | 33398175 |
| 2020-04-11 10:47:00 | The N-terminus of Sec63 is important for stability of the SEC complex and Sec63 is required for proper sorting of membrane proteins in vivo | 31195072 |
| 2019-07-27 11:06:00 | Sec63 tightly associates with Sec61 through interactions in cytosolic, transmembrane, and endoplasmic reticulum -luminal domains, prying open Sec61's lateral gate and translocation pore and thus activating the channel for substrate engagement. | 30545845 |
| 2010-01-21 00:00:00 | The introduction of Sec63 improves secretory proteins in Pichia pastoris secretion 4-7 times. | 16889384 |
| 2010-01-21 00:00:00 | the Sec63p BRL domain is required for assembly of functional endoplasmic reticulum translocons | 16368690 |
| Type | IDs |
|---|---|
| Synonymous | PTL1 |
| Gene |
UniProtKB-ID:
SEC63_YEAST
UniprotKB:
P14906
UniParc:
UPI0000052F91
EMBL:
X16388,
BK006948,
Z75162
EnsemblGenome:
YOR254C
KO:
sce:YOR254C
|
| Nucleutide sequences |
EMBL-CDS:
CAA34424.1,
CAA99476.1,
DAA11021.1
EnsemblGenome_TRS:
YOR254C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR254C
RefSeq:
NP_014897.1
|
| Others |
UniRef100:
UniRef100_P14906
UniRef90:
UniRef90_P14906
UniRef50:
UniRef50_P14906
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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