| Type | Description |
|---|---|
| Definition | kinase non-catalytic C-lobe domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 12:06:00 | The results demonstrated that KNDC1 overexpression possibly inhibited HUVEC activity and function and promoted HUVEC senescence. Mechanistic studies demonstrated that KNDC1 triggered a positive feedback loop, which serves a crucial role in regulating senescence. | 29568929 |
| 2015-01-17 13:16:00 | KNDC1 knockdown promoted HUVEC proliferation via the extracellular signal-regulated kinase signaling pathway and delayed HUVEC senescence by inhibiting the p53-p21-p16 transduction cascade. | 24788352 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association. (HuGE Navigator) | 16385451 |
| Type | IDs |
|---|---|
| Synonymous | C10orf23, RASGEF2, Very-KIND, bB439H18.3, v-KIND |
| Gene |
UniProtKB-ID:
KNDC1_HUMAN
UniprotKB:
Q76NI1
UniParc:
UPI00015D7754,
UPI00001C1ED9,
UPI0000EE7E83,
UPI00003529F7,
UPI0000225CD9,
UPI000007200A
EMBL:
AK131205,
AK074179,
AB051555,
AB000781,
AL445199,
AK057756
Ensembl:
ENSG00000171798
KO:
hsa:85442
|
| Nucleutide sequences |
EMBL-CDS:
BAB71561.1,
BAD12625.1,
BAD18397.1,
BAB85005.1,
BAB21859.1
Gene_ORFName:
hucep-9
Ensembl_TRS:
ENST00000368571,
ENST00000304613
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357560,
ENSP00000304437
RefSeq:
XP_024304013.1,
NP_001334793.1,
NP_001334794.1,
NP_689856.6,
NP_001334795.1,
XP_016872347.1,
XP_016872348.1
|
| Others |
UniRef100:
UniRef100_Q76NI1
UniRef90:
UniRef90_Q76NI1
UniRef50:
UniRef50_Q76NI1
UniGene:
Hs.530685
CCDS:
CCDS7674.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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