| Type | Description |
|---|---|
| Definition | Ca(2+)-dependent cysteine protease MCA1 |
| Date | Results | Publications |
|---|---|---|
| 2016-10-22 12:17:00 | The polyunsaturated fatty acid-producing strain also showed great increase in metacaspase Yca1p activity, suggesting cells could die by caspase-mediated cell death. | 26833421 |
| 2016-09-03 10:42:00 | The yeast metacaspase regulates both proteolytic activities through the ubiquitin-proteasome system and ceramide metabolism as revealed by proteome and metabolome profiling of YCA1-knock-out cells during acetic-acid induced programmed cell death. | 26269384 |
| 2016-02-20 11:53:00 | Using a combination of proteomics and , it was shown that YCA1 deletion down-regulated glycolysis, the TCA cycle and alcoholic fermentation compared with WT cells. | 25697364 |
| 2014-07-12 10:48:00 | Life-span extension and aggregate management by Mca1 was only partly dependent on its conserved catalytic cysteine, which suggests that Mca1 harbors both caspase-dependent and independent functions related to life-span control. | 24855027 |
| 2013-09-14 10:37:00 | protein degradation factors such as Cdc48 co-localize with Yca1 to the insoluble fraction, supporting the hypothesis that Yca1 may act primarily to dissolve or reduce accumulated aggregates. | 23376483 |
| Type | IDs |
|---|---|
| Synonymous | YCA1 |
| Gene |
UniProtKB-ID:
MCA1_YEAST
UniprotKB:
Q08601
UniParc:
UPI0000D796A5
EMBL:
Z75105,
BK006948,
AY692832
EnsemblGenome:
YOR197W
KO:
sce:YOR197W
|
| Nucleutide sequences |
EMBL-CDS:
CAA99410.1,
AAT92851.1,
DAA10972.1
EnsemblGenome_TRS:
YOR197W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR197W
RefSeq:
NP_014840.4
|
| Others |
UniRef100:
UniRef100_A6ZP43
UniRef90:
UniRef90_A6ZP43
UniRef50:
UniRef50_O74477
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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