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854353 LAS17

854353

LAS17

actin-binding protein LAS17

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition actin-binding protein LAS17

研究结论

Date Results Publications
2018-05-05 11:38:00 These studies provide evidence that WASP (Las17) and WIP (Vrp1) play central roles in establishment of a robust multivalent Src homology 3 domain-proline-rich motif network in vivo, giving Actin-related protein 2/3 complex assembly onset at endocytic sites a switch-like behavior. 28813247
2017-07-15 10:27:00 Studies indicate that the WASP homologue Las17 is able to nucleate actin independently of Arp2/3 through the function of G-actin-binding activities in its polyproline region. 27911716
2016-01-16 10:31:00 A model is proposed in which actin filaments bind Vps1 during invagination, and this interaction is important to transduce the force of actin polymerization to the membrane to drive successful scission. 25772449
2015-12-19 11:39:00 LGM has relatively lower potency compared to the previously known Las17 G-actin-binding motif, WH2. 25615019
2013-10-26 12:38:00 Lsb1 and/or Lsb2 full-length proteins inhibit Las17-mediated actin polymerization 23577202

名称对应

Type IDs
Synonymous BEE1
Gene
UniProtKB-ID: LAS17_YEAST
UniprotKB: Q12446
UniParc: UPI000003CA29
EMBL: BK006948, D78487, Z75089
EnsemblGenome: YOR181W
KO: sce:YOR181W
Nucleutide sequences
EMBL-CDS: CAA99390.1, BAA11386.1, DAA10953.1
EnsemblGenome_TRS: YOR181W_mRNA
Protein sequencees
EnsemblGenome_PRO: YOR181W
RefSeq: NP_014824.1
Others
UniRef100: UniRef100_Q12446
UniRef90: UniRef90_Q12446
UniRef50: UniRef50_Q12446

全选

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研究热度

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