| Type | Description |
|---|---|
| Definition | SUMO ligase NFI1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:19:00 | The authors show that Siz2 is enriched at the replication fork barrier (RFB) in the ribosomal DNA (rDNA) and also controls the homeostasis of Tof2 protein. siz2Delta resulted in increased accumulation of total Tof2 in the cell and a consequent increase in the enrichment of Tof2 at the rDNA. | 31776241 |
| 2016-08-27 11:44:00 | double-strand break relocation to the nuclear envelope depends on SUMOylation mediated by the E3 ligases Siz2 and Mms21 | 27056668 |
| 2015-10-24 11:29:00 | DNA break induction, the budding yeast SUMO ligase Siz2 collaborates with the ssDNA-binding complex RPA (replication protein A) to induce the sumoylation of recombination factors and confer damage resistance | 26253534 |
| 2012-07-28 11:29:00 | The sumoylating activity of Siz2 at the nuclear periphery acts to maintain a balance of sumoylation that supports the localization of Sir2/Sir4 to these silent regions. | 22345352 |
| 2011-09-10 12:09:00 | The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. | 21666682 |
| Type | IDs |
|---|---|
| Synonymous | SIZ2 |
| Gene |
UniProtKB-ID:
SIZ2_YEAST
UniprotKB:
Q12216
UniParc:
UPI000012FFC2
EMBL:
U55020,
BK006948,
Z75064,
U33152
EnsemblGenome:
YOR156C
KO:
sce:YOR156C
|
| Nucleutide sequences |
EMBL-CDS:
AAC49642.1,
CAA99362.1,
AAA86121.1,
DAA10929.1
EnsemblGenome_TRS:
YOR156C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR156C
RefSeq:
NP_014799.1
|
| Others |
UniRef100:
UniRef100_Q12216
UniRef90:
UniRef90_Q12216
UniRef50:
UniRef50_Q12216
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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