| Type | Description |
|---|---|
| Definition | Elg1p |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 12:33:00 | Timely removal of PCNA from DNA by the Elg1 complex is important to prevent mutations. The mutator phenotype of elg1Delta is attenuated by PCNA mutants that spontaneously fall off DNA. The elg1Delta mutator phenotype is exacerbated by PCNA mutants that accumulate on DNA due to enhanced electrostatic PCNA-DNA interactions. | 31114918 |
| 2019-03-02 12:25:00 | We find that the major cause of the chromatin organization defects of an ELG1 mutant is PCNA retention on DNA following replication, with Rtt106-Elg1 interaction potentially playing a contributory role. | 30418970 |
| 2018-08-11 10:39:00 | proliferating cell nuclear antigen (PCNA) unloading activity of Elg1 is important for coordinating DNA replication forks with the process of replication-coupled nucleosome assembly to maintain silencing of HML and HMR through S-phase | 29440488 |
| 2017-08-26 12:51:00 | the various roles of Elg1 in genome stability maintenance involve the unloading of both modified and unmodified PCNA. | 28108661 |
| 2016-05-14 12:35:00 | results suggest that Elg1-RLC acts as a general PCNA unloader and is dependent upon DNA ligation during chromosome replication. | 26212319 |
| Type | IDs |
|---|---|
| Synonymous | RTT110 |
| Gene |
UniProtKB-ID:
ELG1_YEAST
UniprotKB:
Q12050
UniParc:
UPI0000053104
EMBL:
BK006948,
U55020,
Z75053,
X94335,
Z75052
EnsemblGenome:
YOR144C
KO:
sce:YOR144C
|
| Nucleutide sequences |
EMBL-CDS:
CAA64062.1,
AAC49631.1,
DAA10918.1,
CAA99351.1,
CAA99348.1
Gene_ORFName:
O3510,
YOR3510C
EnsemblGenome_TRS:
YOR144C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR144C
RefSeq:
NP_014787.3
|
| Others |
UniRef100:
UniRef100_Q12050
UniRef90:
UniRef90_Q12050
UniRef50:
UniRef50_Q12050
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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