| Type | Description |
|---|---|
| Definition | Rab family GTPase VPS21 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 10:59:00 | In this study, we demonstrate that activated Ypt7p localizes to the vacuolar membrane in cells lacking all yeast Rab5 genes. We also show that the vps21Delta ypt7Delta double mutant exhibits a much severer vacuolar phenotype in comparison with the vps21Delta or ypt7Delta single mutant. | 30682048 |
| 2016-04-30 11:32:00 | Data indicate that efficient Vps21 recycling requires both Ypt7 and endosome-vacuole fusion, thus suggesting extended control of a GAP cascade beyond Rab interactions. | 25971802 |
| 2016-04-16 11:13:00 | Finally, three sequential steps of this pathway are delineated: Atg9-dependent exit from the ER en route to autophagy, Ypt1- and core Atgs-mediated pre-autophagsomal-structure organization, and Ypt51-mediated delivery of APs to the vacuole | 26181331 |
| 2015-10-03 10:39:00 | The endocytic traffic branches into two routes to reach the vacuole: a Rab5-dependent vacuolar protein sorting pathway and a Rab5-independent AP-3-mediated pathway. | 24667230 |
| 2013-09-07 10:39:00 | Data indicate that Cells lacking both Vps9 and Muk1 closely phenocopy double and triple knock-out strains lacking Rab5 paralogs. | 23612966 |
| Type | IDs |
|---|---|
| Synonymous | VPS12, VPT12, YPT21, YPT51 |
| Gene |
UniProtKB-ID:
VPS21_YEAST
UniprotKB:
P36017
UniParc:
UPI000013BD32
EMBL:
X94335,
BK006948,
Z29338,
Z74997,
X76173
EnsemblGenome:
YOR089C
KO:
sce:YOR089C
|
| Nucleutide sequences |
EMBL-CDS:
DAA10866.1,
CAA82543.1,
CAA99285.1,
CAA64010.1,
CAA53769.1
Gene_ORFName:
YOR3154C
EnsemblGenome_TRS:
YOR089C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR089C
RefSeq:
NP_014732.1
|
| Others |
UniRef100:
UniRef100_P36017
UniRef90:
UniRef90_P36017
UniRef50:
UniRef50_P36017
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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