| Type | Description |
|---|---|
| Definition | DNA-binding SCF ubiquitin ligase subunit DIA2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:09:00 | Here, using a panel of reporter assays, we demonstrate that mating pheromone stimulates vacuolar targeting of a cytoplasmic reporter protein and that this process depends on Vps34. Through a systematic analysis of F-box deletion mutants, we show that Dia2 is required to sustain pheromone-induced vacuolar targeting | 31399514 |
| 2017-08-12 10:23:00 | Dia2-dependent degradation of Mrc1 is required for replication fork restart in a pathway that includes Sgs1 and Mph1. | 27956499 |
| 2016-06-11 12:01:00 | The tethering of SCF(Dia2) to the replisome progression complex increases the efficiency of ubiquitylation of the Mcm7 subunit of CMG. Correspondingly, loss of tethering is synthetic lethal in combination with a disassembly-defective allele of CDC48. | 26255844 |
| 2014-11-22 11:58:00 | the ubiquitin ligase known as SCF(Dia2) promotes ubiquitylation of CMG helicase during the final stages of chromosome replication in Saccharomyces cerevisiae. | 25342810 |
| 2013-07-27 10:44:00 | Dia2 mediates Mrc1 degradation to help cells resume the cell cycle during recovery from MMS-induced DNA damage in S-phase. | 23172854 |
| Type | IDs |
|---|---|
| Synonymous | YOR29-31 |
| Gene |
UniProtKB-ID:
DIA2_YEAST
UniprotKB:
Q08496
UniParc:
UPI0001C118A2
EMBL:
Z74989,
Z74988,
BK006948,
Z70678
EnsemblGenome:
YOR080W
KO:
sce:YOR080W
|
| Nucleutide sequences |
EMBL-CDS:
DAA10859.2,
CAA99275.1,
CAA99273.1,
CAA94565.1
Gene_ORFName:
YOR29-31
EnsemblGenome_TRS:
YOR080W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR080W
RefSeq:
NP_014723.2
|
| Others |
UniRef100:
UniRef100_Q08496
UniRef90:
UniRef90_Q08496
UniRef50:
UniRef50_Q08496
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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