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85421 Prkd1

85421

Prkd1

protein kinase D1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition protein kinase D1

研究结论

Date Results Publications
2020-07-18 12:31:00 The results suggest that PKD participates in the development of cardiac hypertrophy by regulating autophagy via AKT/mTOR/S6K pathway. 31759056
2017-05-13 20:34:00 siRNA-mediated knockdown of PKD1, PKD2, and PKD3 markedly attenuated YAP nuclear-cytoplasmic shuttling, phosphorylation at Ser(127), and induction of Ctgf and Areg expression in response to GPCR activation. 27369082
2016-08-27 12:50:00 Study delineates the protein kinase D1 binding sites on HSP20 and shows that HSP20 is a substrate for protein kinase D1. 26443497
2014-06-28 10:31:00 PKD1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells. 24647541
2014-03-22 11:09:00 Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2) bind to/regulate activity of Prkd1 (protein kinase D 1) in cardiac/ventricular myocytes; knockdown of Fhl1/FHL2 downregulates Prkd1 activation. 24219103

名称对应

Type IDs
Synonymous Pkcm, Prkcm, nPKC-D1, nPKC-mu
Gene
UniProtKB-ID: KPCD1_RAT
UniprotKB: Q9WTQ1
UniParc: UPI0000DA2A98
EMBL: AABR03049278, AABR03049215, AB020616, AABR03050321, AABR03052344, AABR03048549, AABR03048623, AABR03048825
Ensembl: ENSRNOG00000004165
KO: rno:85421
Nucleutide sequences
EMBL-CDS: BAA78373.1
Ensembl_TRS: ENSRNOT00000068077
Protein sequencees
Ensembl_PRO: ENSRNOP00000063159
RefSeq: XP_017449878.1, XP_006240136.1, NP_001263644.1
Others
UniRef100: UniRef100_Q9WTQ1
UniRef90: UniRef90_Q9WTQ1
UniRef50: UniRef50_Q62101
UniGene: Rn.144619, Rn.234516

全选

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研究热度

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