| Type | Description |
|---|---|
| Definition | Rad2 family nuclease EXO1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:53:00 | We show here that Exo1 phosphorylation is Dun1-independent and Rad53-dependent in response to DNA damage or dNTP depletion, and in both situations Exo1 is similarly phosphorylated at multiple sites. | 32020204 |
| 2019-08-31 11:31:00 | By conditionally depleting lagging-strand nucleases and directly analyzing Okazaki fragments synthesized in vivo in Saccharomyces cerevisiae, we conduct a systematic evaluation of the impact of Rad27, Dna2 and Exo1 on lagging-strand synthesis. We find that Rad27 processes the majority of lagging-strand flaps, with a significant additional contribution from Exo1 but not from Dna2. | 30541106 |
| 2019-07-06 10:05:00 | A harmless head-on replication-transcription clash resolution requires the fine-tuning of origin firing and coordination among Sen1, Exo1, Mre11 and Mrc1-Ctf4 complexes. | 29059325 |
| 2019-06-29 10:26:00 | This function requires interaction with the replication clamp, proliferating cell nuclear antigen, facilitating its recruitment to damage sites, and complements the activity of an exonuclease, Exo1, in the processing of post-replicative daughter-strand gaps in preparation for template switching | 30107417 |
| 2019-05-04 10:24:00 | MRX creates a specific DNA end structure that promotes Exo1 resection activity by facilitating the persistence of this nuclease on the DSB ends, uncovering a novel MRX function in DSB resection. | 29925516 |
| Type | IDs |
|---|---|
| Synonymous | DHS1 |
| Gene |
UniProtKB-ID:
EXO1_YEAST
UniprotKB:
P39875
UniParc:
UPI000012A361
EMBL:
U86134,
X87331,
BK006948,
Z74941,
S69545
EnsemblGenome:
YOR033C
KO:
sce:YOR033C
|
| Nucleutide sequences |
EMBL-CDS:
DAA10815.1,
CAA60749.1,
CAA99223.1,
AAB47428.1,
AAC60570.1
Gene_ORFName:
OR26.23
EnsemblGenome_TRS:
YOR033C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR033C
RefSeq:
NP_014676.1
|
| Others |
UniRef100:
UniRef100_P39875
UniRef90:
UniRef90_P39875
UniRef50:
UniRef50_P39875
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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