| Type | Description |
|---|---|
| Definition | exosome nuclease subunit RRP6 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-12 11:56:00 | Here, we investigated the interplay of exosome-associated 3'-5' exonucleases DIS3 and RRP6 in rRNA processing and by-product elimination in human cells | 30266864 |
| 2017-09-02 11:01:00 | 3' phosphate RNA is not a substrate for Rrp6 but is readily degraded by Rrp44 in the nuclear exosome. | 27818140 |
| 2017-08-12 10:14:00 | Data suggest that, in nuclear exosomes, karyopherins are bound to the Rrp6 complex; Srp1, Kap95, and Sxm1 appear to be the most important karyopherins for nuclear import of Rrp6. (Rrp6 = exosome nuclease subunit RRP6; Srp1 = karyopherin alpha kap60; Kap95 = karyopherin beta Kap95; Sxm1 = karyopherin Kap108) | 28539363 |
| 2017-04-29 12:35:00 | Rrp41 mutations blocked substrate passage through the channel to Rrp44 only for cytoplasmic mRNAs, supporting the predicted widening of the lumen in the Rrp6-associated.Many exosome substrates exhibited clear preferences for a specific path to Rrp44. Both threading and direct access routes involve the RNA helicase Mtr4Rrp41 mutations blocked substrate passage through the channel to Rrp44 only for cytoplasmic mRNAs, suppor | 28355211 |
| 2016-10-22 11:55:00 | Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination | 26612606 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RRP6_YEAST
UniprotKB:
Q12149
UniParc:
UPI0000052F38
EMBL:
U43491,
BK006948,
AY692850,
Z74909
EnsemblGenome:
YOR001W
KO:
sce:YOR001W
|
| Nucleutide sequences |
EMBL-CDS:
DAA10783.1,
AAC49480.1,
CAA99189.1,
AAT92869.1
EnsemblGenome_TRS:
YOR001W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR001W
RefSeq:
NP_014643.1
|
| Others |
UniRef100:
UniRef100_Q12149
UniRef90:
UniRef90_Q12149
UniRef50:
UniRef50_Q12149
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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