| Type | Description |
|---|---|
| Definition | exosome catalytic subunit DIS3 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:26:00 | The DIS3 mutations do not increase DNA damage or RNA processing defects that lead to the accumulation of polyadenylated RNA in the nucleus and specific DIS3 activities support mitotic fidelity in yeast. | 30724665 |
| 2017-09-02 11:01:00 | 3' phosphate RNA is not a substrate for Rrp6 but is readily degraded by Rrp44 in the nuclear exosome. | 27818140 |
| 2017-04-29 12:35:00 | Rrp41 mutations blocked substrate passage through the channel to Rrp44 only for cytoplasmic mRNAs, supporting the predicted widening of the lumen in the Rrp6-associated.Many exosome substrates exhibited clear preferences for a specific path to Rrp44. Both threading and direct access routes involve the RNA helicase Mtr4 | 28355211 |
| 2014-08-16 10:49:00 | While the molecular functions of Rrp44 and the RNA exosome have been extensively characterized, our studies characterize how this molecular function affects the physiology of the organism. | 24860016 |
| 2013-06-15 11:35:00 | Rrp41 mutation caused accumulation of nuclear and cytoplasmic exosome substrates including the non-stop decay reporter, for which degradation is dependent on either endonucleolytic or exonucleolytic Dis3 activities. | 23404585 |
| Type | IDs |
|---|---|
| Synonymous | MTR17, RRP44 |
| Gene |
UniProtKB-ID:
RRP44_YEAST
UniprotKB:
Q08162
UniParc:
UPI0000052F2F
EMBL:
D76430,
BK006948,
Z74763
EnsemblGenome:
YOL021C
KO:
sce:YOL021C
|
| Nucleutide sequences |
EMBL-CDS:
DAA10760.1,
BAA11176.1,
CAA99021.1
Gene_ORFName:
O2197
EnsemblGenome_TRS:
YOL021C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOL021C
RefSeq:
NP_014621.1
|
| Others |
UniRef100:
UniRef100_Q08162
UniRef90:
UniRef90_Q08162
UniRef50:
UniRef50_Q08162
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员