| Type | Description |
|---|---|
| Definition | DNA repair ATPase SMC5 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:01:00 | Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction. | 33301732 |
| 2020-02-22 10:37:00 | Our findings thus indicate a direct role for SUMO in Pol2-mediated DNA synthesis and a molecular basis for Smc5/6-mediated regulation of genome stability | 31765372 |
| 2019-02-23 13:08:00 | These results reveal a mechanism to enhance a SUMO E3 ligase activity by direct DNA binding and to restrict sumoylation in the vicinity of those Smc5/6-Nse2 molecules engaged on DNA. | 29769404 |
| 2018-06-23 10:37:00 | Data suggest that aSmc5/6 likely links rDNA stability to overall mitotic growth. | 29360860 |
| 2018-04-07 11:40:00 | Our findings reveal a requirement for the Smc5/6 complex, including Mms21/Nse2 mediated sumoylation, and topoisomerase-1 (Top1), for maintaining stability of a chromosome having low origin density and suggest a functional cooperation between the Smc5/6 complex and Top1 in maintenance of topologically challenged chromosomes prone to replication fork collapse or accumulation of torsional stress | 28204881 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SMC5_YEAST
UniprotKB:
Q08204
UniParc:
UPI000006AC72
EMBL:
Z74776,
BK006948
EnsemblGenome:
YOL034W
KO:
sce:YOL034W
|
| Nucleutide sequences |
EMBL-CDS:
CAA99034.1,
DAA10747.1
EnsemblGenome_TRS:
YOL034W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOL034W
RefSeq:
NP_014608.1
|
| Others |
UniRef100:
UniRef100_Q08204
UniRef90:
UniRef90_Q08204
UniRef50:
UniRef50_Q08204
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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