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854106 GAL11

854106

GAL11

Gal11p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Gal11p

研究结论

Date Results Publications
2020-12-05 12:58:00 The Polymorphic PolyQ Tail Protein of the Mediator Complex, Med15, Regulates the Variable Response to Diverse Stresses. 32164312
2020-09-19 16:23:00 Med15: Glutamine-Rich Mediator Subunit with Potential for Plasticity. 31036407
2019-09-21 12:34:00 Authors find that the large Gcn4-Med15 complex is heterogeneous and contains nearly all possible AD-ABD interactions. Gcn4-Med15 forms via a dynamic fuzzy protein-protein interface, where ADs bind the ABDs in multiple orientations via hydrophobic regions that gain helicity. 29562181
2014-11-29 10:08:00 The central activation domain (cAD) of Gcn4 functions through a sequence-specific motif. Optimizing this motif by inserting additional hydrophobic residues creates ADs that bind the Mediator subunit Gal11 via a "fuzzy" protein interface. 25122681
2013-06-29 11:28:00 Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16. 23447536

名称对应

Type IDs
Synonymous ABE1, MED15, RAR3, SDS4, SPT13
Gene
UniProtKB-ID: MED15_YEAST
UniprotKB: P19659
UniParc: UPI000005314F
EMBL: M22481, X91067, BK006948, Z74793
EnsemblGenome: YOL051W
KO: sce:YOL051W
Nucleutide sequences
EMBL-CDS: AAA34622.1, DAA10733.1, CAA62537.1, CAA99056.1
EnsemblGenome_TRS: YOL051W_mRNA
Protein sequencees
EnsemblGenome_PRO: YOL051W
RefSeq: NP_014591.1
Others
UniRef100: UniRef100_P19659
UniRef90: UniRef90_P19659
UniRef50: UniRef50_P19659

全选

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研究热度

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