| Type | Description |
|---|---|
| Definition | NKD inhibitor of WNT signaling pathway 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:52:00 | NKD2 phosphorylation by promotes cell-surface delivery of TGFalpha and increased EGFR activation. | 30941853 |
| 2019-03-09 10:40:00 | The experiments in vitro suggested that knockdown of ZFAS1 repressed bladder cancer cell proliferation via up-regulating KLF2 and NKD2 expression, and inhibited cell migration and invasion via down-regulating ZEB1 and ZEB2 expression. | 29678899 |
| 2019-02-09 12:44:00 | Reduced expression of NKD2 correlated with hyperactivation of the Wnt/beta-catenin pathway and doxorubicin resistance in hepatocellular carcinoma cells | 29126834 |
| 2018-04-07 11:26:00 | ZFAS1 over-expression confers an oncogenic function in gastric cancer and this function is partly dependent on repressing KLF2 and NKD2 | 27246976 |
| 2017-11-04 13:11:00 | NKD2 is frequently methylated in human esophageal cancer, and the expression of NKD2 is regulated by promoter region methylation. NKD2 suppresses esophageal cancer progression by inhibiting Wnt signaling both in vitro and in vivo. | 27374455 |
| Type | IDs |
|---|---|
| Synonymous | Naked2 |
| Gene |
UniProtKB-ID:
NKD2_HUMAN
UniprotKB:
Q969F2
UniParc:
UPI000006FE8C,
UPI0000073E19
EMBL:
BC004940,
AF358137,
BC012176,
AB062887
Ensembl:
ENSG00000145506,
ENSG00000276920
KO:
hsa:85409
|
| Nucleutide sequences |
EMBL-CDS:
AAK57486.1,
BAB70501.1,
AAH12176.1,
AAH04940.1
Ensembl_TRS:
ENST00000296849,
ENST00000610777,
ENST00000274150,
ENST00000616539
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296849,
ENSP00000482896,
ENSP00000274150,
ENSP00000479003
RefSeq:
NP_001258011.1,
NP_149111.1,
XP_016865489.1,
XP_005248439.1,
XP_005248440.1,
XP_011512452.1
|
| Others |
UniRef100:
UniRef100_Q969F2
UniRef90:
UniRef90_Q969F2
UniRef50:
UniRef50_Q969F2
UniGene:
Hs.240951
CCDS:
CCDS59486.1,
CCDS3859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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