| Type | Description |
|---|---|
| Definition | histone deacetylase HST1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 11:23:00 | ChIP experiments with the BNA2 promoter indicated that Mac1 works with Hst1-containing repressor complexes to silence BNA expression. | 30760525 |
| 2018-07-21 12:03:00 | In the absence of Set1, there is loss of the DNA-binding transcriptional regulator Sum1 and the associated histone deacetylase Hst1 from chromatin in a locus-specific manner | 29066473 |
| 2017-03-11 10:08:00 | study demonstrates that Hst1, the closest Sir2 paralogue, deacetylates the acetylated lysine 16 of histone H4 (H4K16Ac) and represses PMA1 transcription in the sir2Delta pde2Delta mutant. Collectively,results suggest that Hst1 can substitute for Sir2 by deacetylating H4K16Ac only in the sir2Delta pde2Delta | 28120189 |
| 2012-03-17 12:24:00 | Crystals of HST1 grown by the hanging-drop vapour-diffusion method diffracted to 2.90 A resolution and belonged to space group P2(1), with unit-cell parameters a = 40.2, b = 101.7, c = 43.9 A, beta = 103.9 degrees | 22139171 |
| 2011-11-12 12:17:00 | Sir2 and Hst1 subfunctionalized by acquiring complementary inactivating mutations in these interaction domains. | 21690292 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HST1_YEAST
UniprotKB:
P53685
UniParc:
UPI0000053267
EMBL:
Z74810,
BK006948,
U39041,
L47120
EnsemblGenome:
YOL068C
KO:
sce:YOL068C
|
| Nucleutide sequences |
EMBL-CDS:
CAA99078.1,
DAA10715.1,
AAA81033.1,
AAB38430.1
EnsemblGenome_TRS:
YOL068C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOL068C
RefSeq:
NP_014573.1
|
| Others |
UniRef100:
UniRef100_P53685
UniRef90:
UniRef90_P53685
UniRef50:
UniRef50_P53685
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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