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854034 PAP2

854034

PAP2

non-canonical poly(A) polymerase PAP2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition non-canonical poly(A) polymerase PAP2

研究结论

Date Results Publications
2014-10-18 11:34:00 Results show that the Nrd1-Trf4 interaction is required for optimal exosome activity in vivo and for the stimulation of polyadenylation of NNS targets by TRAMP in vitro. 25066235
2014-01-04 10:10:00 Cotranscriptional recruitment of RNA exosome cofactors Rrp47p and Mpp6p and two distinct Trf-Air-Mtr4 polyadenylation (TRAMP) complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant messenger 24047896
2012-08-18 10:43:00 Data show that the unwinding activity of Mtr4p is significantly stimulated by Trf4p/Air2p, but the stimulation of Mtr4p does not depend on ongoing polyadenylation. 22532666
2011-12-17 11:40:00 Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex. 21878619
2010-04-12 12:17:00 Data suggest that neither the poly(A) polymerase activity of Trf4 nor the helicase activity of Mtr4 plays a role in the enhancement of RNA degradation by the nuclear exosome component Rrp6. 19955569

名称对应

Type IDs
Synonymous TRF4
Gene
UniProtKB-ID: PAP2_YEAST
UniprotKB: P53632
UniParc: UPI000005309C
EMBL: Z74857, Z48149, U31355, AY723865, BK006948
EnsemblGenome: YOL115W
KO: sce:YOL115W
Nucleutide sequences
EMBL-CDS: CAA88145.1, CAA99134.1, DAA10668.1, AAU09782.1, AAC49091.1
Gene_ORFName: HRC584, O0716
EnsemblGenome_TRS: YOL115W_mRNA
Protein sequencees
EnsemblGenome_PRO: YOL115W
RefSeq: NP_014526.1
Others
UniRef100: UniRef100_P53632
UniRef90: UniRef90_P53632
UniRef50: UniRef50_P53632

全选

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研究热度

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