| Type | Description |
|---|---|
| Definition | translation initiation factor eIF4E |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo. | 32469309 |
| 2019-10-05 10:54:00 | We propose that the eIF4E/p20/mRNA complex serves as a stable depository of mRNAs existing in a dynamic equilibrium with other complexes such as eIF4E/eIF4G (required for translation) and eIF4E/Eap1 (required for mRNA degradation) | 29712996 |
| 2019-07-06 10:32:00 | Crystal structures of the yeast eIF4E bound to two yeast 4E-BPs, p20 and Eap1p, as well as crystal structures of a fungal eIF4E-eIF4G complex, were determined. Highly specialized structural motifs serve to modulate the affinity of protein-protein interactions regulating cap-dependent translation initiation in fungi.The canonical and non-canonical motifs in 4E-BPs and eIF4G contribute differently to the affinity for eIF4E. | 30053226 |
| 2015-12-19 10:10:00 | Closed-loop model of mRNA translation is prevalent for eIF4E/4G-bound but unexpectedly sparse for PAB1-bound mRNAs. | 25826658 |
| Type | IDs |
|---|---|
| Synonymous | TIF45 |
| Gene |
UniProtKB-ID:
IF4E_YEAST
UniprotKB:
P07260
UniParc:
UPI000004F966
EMBL:
X84036,
AY692936,
M15436,
M21620,
M29251,
BK006948,
Z74881
EnsemblGenome:
YOL139C
KO:
sce:YOL139C
|
| Nucleutide sequences |
EMBL-CDS:
CAA58854.1,
AAT92955.1,
AAA34588.1,
CAA99160.1,
AAA34480.1,
DAA10646.1,
AAA34587.1
EnsemblGenome_TRS:
YOL139C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOL139C
RefSeq:
NP_014502.1
|
| Others |
UniRef100:
UniRef100_P07260
UniRef90:
UniRef90_P07260
UniRef50:
UniRef50_P07260
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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